Comparative Evaluation of Calcium Hydroxide as an Intracanal Medicament with Aqueous and Viscous Based Vehicles in Patients with Pulpal Necrosis and Symptomatic Apical Periodontitis: Impact on Postoperative Pain and Healing Outcome
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Differences expected in the level of post-operative pain & healing
研究概览
简要总结
Objective: This study aimed to evaluate the effect of calcium hydroxide used as an intracanal medicament with aqueous and viscous based vehicles on postoperative pain and healing outcomes in patients diagnosed with pulpal necrosis and symptomatic apical periodontitis.
Methods: A randomized controlled trial was conducted with a sample of patients presenting with pulpal necrosis and symptomatic apical periodontitis. The participants were divided into two groups: one receiving calcium hydroxide with an aqueous vehicle and the other with a viscous vehicle. The medicament was applied during root canal treatment. Postoperative pain levels and healing outcomes were assessed using pain scales and radiographic examination, respectively.
Results: Both groups demonstrated effective delivery of calcium hydroxide to the affected area. Postoperative pain levels significantly decreased in both groups compared to baseline, with no statistically significant difference between the two groups. Radiographic examination revealed comparable periapical healing outcomes in both groups.
Conclusion: Calcium hydroxide used as an intracanal medicament with aqueous and viscous based vehicles showed similar efficacy in reducing postoperative pain and promoting healing in patients with pulpal necrosis and symptomatic apical periodontitis. The choice of vehicle can be based on clinical preference. Further research is needed to explore additional factors influencing postoperative pain and healing outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •Mandibular molars diagnosed with Pulp necrosis and Symptomatic apical periodontitis and Teeth with mature apices.
排除标准
- •Patients who had taken analgesics or anti-inflammatory drugs within the last 12 hours, Teeth with calcified canals and aberrant root canal morphology, Pregnant or lactating patients, Patients with history of allergy to any of the components of local anesthesia, Teeth with previous RCT, Severely damaged or mutilated teeth, Patients with any systemic diseases,.
结局指标
主要结局
Differences expected in the level of post-operative pain & healing
时间窗: post operative pain will be evaluated at 6, 24,48 & 72 hours | Periapical healing will be evaluated at 3,6,9 & 12 months
次要结局
- Differences expected in the level of post operative pain & healing in patients of pulpal necrosis & symptomatic apical periodontitis after placing calcium hydroxide with aqueous & viscous vehicles(Post operative pain will be evaluated at 6, 24, 48 &72 hours)