Effect of Calcium Hydroxide as an intracanal medicament with aqueous and viscous based vehicles in patients with pulpal necrosis and symptomatic apical periodontitis on post operative pain and healing outcome

Phase 2

Not yet recruiting

Conditions: Acute apical periodontitis of pulpal origin,

Registration Number: CTRI/2023/07/055396

Lead Sponsor: Lubhansha Kumar

Brief Summary: Objective: This study aimed to evaluate the effect of calcium hydroxide used as an intracanal medicament with aqueous and viscous based vehicles on postoperative pain and healing outcomes in patients diagnosed with pulpal necrosis and symptomatic apical periodontitis.

Methods: A randomized controlled trial was conducted with a sample of patients presenting with pulpal necrosis and symptomatic apical periodontitis. The participants were divided into two groups: one receiving calcium hydroxide with an aqueous vehicle and the other with a viscous vehicle. The medicament was applied during root canal treatment. Postoperative pain levels and healing outcomes were assessed using pain scales and radiographic examination, respectively.

Results: Both groups demonstrated effective delivery of calcium hydroxide to the affected area. Postoperative pain levels significantly decreased in both groups compared to baseline, with no statistically significant difference between the two groups. Radiographic examination revealed comparable periapical healing outcomes in both groups.

Conclusion: Calcium hydroxide used as an intracanal medicament with aqueous and viscous based vehicles showed similar efficacy in reducing postoperative pain and promoting healing in patients with pulpal necrosis and symptomatic apical periodontitis. The choice of vehicle can be based on clinical preference. Further research is needed to explore additional factors influencing postoperative pain and healing outcomes.

Detailed Description: Not available

Recruitment & Eligibility

Status: Not Yet Recruiting

Sex: All

Target Recruitment: 50

Inclusion Criteria

Mandibular molars diagnosed with Pulp necrosis and Symptomatic apical periodontitis and Teeth with mature apices.

Exclusion Criteria

Patients who had taken analgesics or anti-inflammatory drugs within the last 12 hours, Teeth with calcified canals and aberrant root canal morphology, Pregnant or lactating patients, Patients with history of allergy to any of the components of local anesthesia, Teeth with previous RCT, Severely damaged or mutilated teeth, Patients with any systemic diseases,.

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Differences expected in the level of post-operative pain & healing	post operative pain will be evaluated at 6, 24,48 & 72 hours \| Periapical healing will be evaluated at 3,6,9 & 12 months

Secondary Outcome Measures

Name	Time	Method
Differences expected in the level of post operative pain & healing in patients of pulpal necrosis & symptomatic apical periodontitis after placing calcium hydroxide with aqueous & viscous vehicles	Post operative pain will be evaluated at 6, 24, 48 &72 hours

Trial Locations

Locations (1): Manav Rachna Dental College
🇮🇳
Faridabad, HARYANA, India
Manav Rachna Dental College
🇮🇳Faridabad, HARYANA, India
Dax Abraham
Principal investigator
9910433111
daxabraham.mrdc@mrei.ac.in