CTRI/2022/10/046482RecruitingNot Applicable
Correlation of delta rectus femoris thickness with weaning failure in critically ill mechanically ventilated patients
Bharati Hospital and Research center1 site in 1 country136 target enrollmentStarted: October 15, 2022Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Recruiting
- Sponsor
- Enrollment
- 136
- Locations
- 1
- Primary Endpoint
- Weaning Failure after first spontaneous breathing trial
Study Overview
Brief Summary
There are small studies suggesting a correlation between difference in skeletal muscle thickness (rectus femoris + vastus intermedius), diaphragmatic thickness and excursion with weaning failure. As measurement of diaphragmatic thickness and excursion is difficult we have planned to determine correlation between USG guided delta rectus femoris muscle thickness and weaning failure in critically ill mechanically ventilated patients.
Study Design
- Study Type
- Observational
Eligibility Criteria
- Ages
- 18.00 Year(s) to 99.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •i.Age above 18 years.
- •ii.Patients requiring more than 24 hours of mechanical ventilation on admission or within 24 hours of admission.
Exclusion Criteria
- •i.Patients with trauma to bilateral thighs for eg- degloving injuries, burns, fractures etc.
- •ii.Patients with known neuromuscular disorders, stroke, previously diagnosed critical illness neuropathy, unilateral or bilateral swelling in the legs.
- •iii.Patients with history of chronic organ failures, malignancy and pregnancy.
Outcomes
Primary Outcomes
Weaning Failure after first spontaneous breathing trial
Time Frame: At baseline, within 24 hours of first spontaneous breathing trial
Secondary Outcomes
- •To measure length of ICU stay, ventilator free days and 28-day mortality in all patients.(2 years)
Investigators
Study Sites (1)
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