Prevalence of Hyponatremia in Dengue Infected Patients: Relationship With Systemic Inflammation.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 530
- 试验地点
- 2
- 主要终点
- Admission to the hospital
研究概览
简要总结
Prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
详细描述
Background Dengue infection is becoming more prevalent worldwide and is associated with systemic inflammation. Systemic Inflammation is associated with non-osmotic release of ADH.
Methods: Participants conducted a prospective cohort study in patients with newly diagnosed dengue infection at Hospital Posadas in Argentina, between January 1, 2016, and November 1, 2023. Diagnosis was confirmed by IgM serology or PCR. Hyponatremia was defined as serum sodium concentration ≤135 mEq/L.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis confirmed by PCR, non structural protein 1 (NS1) antigen or IgM serology.
- •Plasma sodium at admission.
排除标准
- 未提供
结局指标
主要结局
Admission to the hospital
时间窗: between january 1, 2023 and november 1, 2023
Risk for admission to the hospital
次要结局
未报告次要终点
研究者
Ladislao Diaz Ballve
Principal Investigator
Hospital Nacional Profesor Alejandro Posadas