Assessment of Adherence of Rheumatoid Arthritis Patients to Methotrexate and Its Effect on Quality of Life.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 300
- 试验地点
- 1
- 主要终点
- Assessment of Rheumatoid Arthritis patient adherence to Methotrexate and its effect on quality of life
研究概览
简要总结
This study was conducted for assessment of adherence of Rheumatoid Arthritis patients to Methotrexate as a gold standard drug for treatment of R.A. Moreover, evaluating the effect of drug adherence to patient quality of life.
详细描述
Rheumatoid arthritis one of most common autoimmune diseases. characterized by numerous complications which may affect patient quality of life. Hence, this review aim to search the relation between patient"s drug adherence and clinical health outcome. our review utilizing survey as a tool to collect needed data from rheumatoid patients. survey consisted of number of questions , participants were required to answer these questions. participation to this questionnaire was optional.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The study was carried out among all RA patients (adults patients ≥ 18 years).
- •Patients not suffering from severe mental disorders.
- •Patients with a disease duration from (1-5) years.
- •Patients on MTX treatment from (1-5) years.
- •Patients taking MTX alone or in combination with other DMARDs.
排除标准
- •Patient who on MTX for more than 5 years
- •Patient who have complications like:-
- •History of liver or kidney disease
- •Diabetic patients
- •Hypertensive patients
- •Bone marrow hypoplasia
- •Leukopenia or significant anemia
- •Peptic ulcer or any GIT problems
- •Hereditary alopecia.
结局指标
主要结局
Assessment of Rheumatoid Arthritis patient adherence to Methotrexate and its effect on quality of life
时间窗: Baseline
aim of this study was to measure Rheumatoid Arthritis patient adherence to MTX. A descriptive cross-sectional study was conducted on 300 RA patients administrating MTX for at least one year. Direct interview was used to complete the survey. The documented data were demographics (age, education , sex, work status). Patients' adherence to MTX as well as predictors for non-adherence.This investigational clinical study was conducted on RA outpatient clinic. Clinical parameters such as disease duration, duration on MTX therapy in years and current dose of MTX in milligrams per week were all documented.Structured questionnaire was designed to assessed the following areas: MTX side effects, patient adherence towards MTX, functional disability and patient awareness towards MTX. Patients were questioned about the prevalence of gastrointestinal adverse effects related to MTX. All data was collected from one direct interview with each RA patient.
次要结局
未报告次要终点
研究者
Marwa Mohamed Abd El-Maboud
Marwa.M.Ad El-Maboud
Beni-Suef University