Functional effects of treatment of organ confined prostate cancer on lower urinary tract
Completed
- Conditions
- urinary urgency /urinary leak10004994
- Registration Number
- NL-OMON33683
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Proven organ confined prostate cancer with indication for curative treatment
Exclusion Criteria
(locally) advanced prostaat carcinoom
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Urodynamic changes in comparison with the baseline:<br /><br><br /><br>• Maximum flow rate<br /><br>• Volume of the first muscle instability.<br /><br>• Amplitude of the first instable contraction<br /><br>• Amplitude of the maximal instable contraction<br /><br>• Volume of the maximal instable contraction<br /><br>• Volume of the first desire to urinate<br /><br>• Bladder compliance before and after brachytherapie<br /><br>• Maximale urethral closure pressure (MUCP)<br /><br>• Urethrale pressure profile-length<br /><br>• Urethrale resistance/URA_BOOI<br /><br>• Schafer graad<br /><br>• Bladder contractility index:PQmax+5xQmax, Wmax, WQmax<br /><br>* Post-void residue<br /><br>* 24 uur padtest</p><br>
- Secondary Outcome Measures
Name Time Method <p><br /><br><br /><br>The subjetive changes of parameters in comparison with the baseline:<br /><br><br /><br>International Prostate Symptom Score (IPSS)<br /><br>• Frequentie- volume Chart<br /><br>• EPIC-MICTURATION<br /><br>• EPIC-INTESTINAL SYMPTOMS<br /><br>• EPIC-SEXUALITY</p><br>