Evaluation of the effect of intra-articular injection of dexamethasone and vitamin D compared to injection of dexamethasone alone on signs of knee osteoarthritis
Phase 3
Recruiting
- Conditions
- Knee osteoarthritis with grade 2 and 3.M16.30
- Registration Number
- IRCT20220526054993N1
- Lead Sponsor
- Alborz University of Medical Science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 154
Inclusion Criteria
Age between 40 to 65
Bilateral knee osteoarthritis
Having score 2 and 3 of KL system radiography
Completion of informed consent form to enter the study
Exclusion Criteria
Presence of secondary cause for knee osteoarthritis
Allergic history to dexamethasone or vitamin D
History of diabetes or coagulopathy
History or manifestation of joint infection or deformity
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The score obtained in the WOMAC knee score to evaluate the degree of osteoarthritis. Timepoint: Before intervention and 1, 3, and 6 month after intervention. Method of measurement: WOMAC knee score.
- Secondary Outcome Measures
Name Time Method The amount of analgesic consumption. Timepoint: Before intervention and 1, 3, and 6 mouths after intervention. Method of measurement: Questionnaire to assess the number of analgesics consumed per week.;Range of motion of the knee. Timepoint: Before intervention and 1, 3, and 6 mouths after intervention. Method of measurement: Clinical examination.;Joint pain. Timepoint: Before intervention and 1, 3, and 6 mouths after intervention. Method of measurement: The size of joint pain in millimeters on the scaled ruler.