A Danish Nationwide Longitudinal Registered Based Study on Prevalence, Treatment Patterns and Disease Trajectories of Periodontitis and Co-morbidities 'PlanPerioMed'
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 4,000,000
- 主要终点
- Effect on medical diseases
研究概览
简要总结
The project (PlanPerioMed) is a register-based study evaluating the associations and patterns of health care delivery between periodontitis and medical diseases using data from the Danish dental record system Dentalsuite (Plandent A/S) and national Danish health care registries with three overall hypotheses/ aims:
- Determine the extent to which periodontitis in registry data is associated with more odontological treatment services and treatment frequency.
- Determine if patients with systemic diseases attend dentists more frequently and receive more treatment services per patient than the population without these diseases.
- Determine to which extent periodontitis and received periodontal treatment affects the risk of medical diseases.
The study will focus on association and trajectories of periodontitis and its treatment with three medical diseases, namely, Type 2 Diabetes Mellitus (Type 2 DM), Cardiovascular Diseases (CVD) and Rheumatoid Arthritis (RA). The dataset consists of approximately 4,000,000 people aged between 18 and 99 years attending private practice in Denmark. The results from PlanPerioMed study are likely to have ramifications for treatment guidelines for other periodontitis comorbidities, e.g. CVD and DM, and will thereby improve the quality of life for a wide range of patients and reduce long-term societal health care expenses related to periodontitis and its comorbidities.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 99 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Subjects with clinical registrations of DMFT, periodontal status and corresponding treatment codes
- •Self-reported systemic diseases including Diabetes Mellitus Type 2, Cardiovascular Diseases and Rheumatoid Arthritis
- •Subjects with Clinical Attachment Loss>=3mm, Probing Depth >= 3mm and bleeding on probing (as defined by World Workshop 2017- criteria for periodontitis) in clinical examination will be included in the study population.
排除标准
- •Subjects with more than 32 teeth
- •Subjects with no clinical registrations
结局指标
主要结局
Effect on medical diseases
时间窗: 25 years
Risk of medical diseases based on periodontal disease extent and received periodontal treatment
Treatment frequency and type of treatment services
时间窗: 25 years
Number of treatment and odontological treatment services due to periodontitis
Treatment frequency and type of treatment services among patients with medical diseases
时间窗: 25 years
Number of treatment and odontological treatment services among patients with medical diseases due to periodontitis
次要结局
未报告次要终点
研究者
Christian Damgaard
Associate professor, Head of Section
University of Copenhagen
