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临床试验/ACTRN12615000169549
ACTRN12615000169549招募中4 期

The effect of doxycycline and prednisone on the microbiome of patients with chronic sinusitis, a study by the Department of Surgery, University of Auckland.

Associate Professor Richard Douglas0 个研究点目标入组 20 人开始时间: 2015年2月20日最近更新:
适应症

试验速览

阶段
4 期
状态
招募中
发起方
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Treatment
盲法
Blinded (masking used)

入排标准

年龄范围
16 Years 至 o limit(—)
性别
All

入选标准

  • Patients newly diagnosed with CRS and are eligible for sinus surgery.
  • Patients providing fully informed consent to participate in this study.

排除标准

  • Patients who are acutely unwell.
  • Patients with cystic fibrosis.
  • Patients with a history of previous nasal surgery.
  • Children (<16 years)
  • Immunodeficiency (congenital or acquired)
  • Congenital mucociliary problems (e.g. primary ciliary dyskinesia)
  • Non-invasive and invasive fungal sinus disease
  • Systemic vasculitis and granulomatous diseases
  • History of cocaine abuse;
  • Patients requiring sinus surgery for neoplasia
  • Patients unable to consent (e.g. lack of mental capacity)

研究者

发起方
Associate Professor Richard Douglas

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