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临床试验/NCT05727254
NCT05727254已完成不适用

Agility Training for Older Adults: A Randomized Controlled Trial

Oliver Faude2 个研究点 分布在 1 个国家目标入组 48 人开始时间: 2022年7月13日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
Oliver Faude
入组人数
48
试验地点
2
主要终点
Isometric knee-extension strength

研究概览

简要总结

In this randomized controlled trial the effect of 4 months of multi-component (strength, balance, cognition, endurance) exercise training intervention on measures of neuromuscular performance, cognition, and endurance as well as neural adaptations on a central and peripheral level is investigated. 40 subjects are recruited that are generally health and between 60 and 80 years of age. The interventions is based around exercises, where different tasks have to be solved simultaneously rather than serially, as has previously been done.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

盲法说明

Due to the nature of the study (exercise intervention) no masking of participants and intervention providers is possible.

入排标准

年龄范围
60 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • willing to be randomized to either arm
  • ability to travel to the sports facility twice a week
  • understanding the german language

排除标准

  • smoking, obesity
  • history of cardiovascular, pulmonary or chronic inflammatory disease
  • vision impairments
  • orthopaedic problems preventing them from participating in an exercise program
  • history of osteoporosis or recent low trauma fracture
  • less than two weeks during the intervention period
  • not have taken part in a structured exercise program more than once a week in the past three months

结局指标

主要结局

Isometric knee-extension strength

时间窗: 16 weeks

Strength in torque (N\*m) of the quadriceps femoris muscle. Measured on an isokinetic device in an isometric condition.

次要结局

  • Cognitive Processing Speed(16 weeks)
  • Balance Performance(16 weeks)
  • Isometric knee-flexion strength(16 weeks)
  • Cognitive Impulsiveness(16 weeks)
  • Pulse Wave Velocity(16 weeks)
  • Retinal vessel diameter(16 weeks)
  • Depression(16 weeks)
  • Hand Grip Strength(16 weeks)
  • Blood Pressure(16 weeks)
  • Fall Efficacy(16 weeks)
  • Sleep Disturbances(16 weeks)
  • Stress(16 weeks)
  • Counter movement jump power(16 weeks)
  • Quality of Life Questionnaire(16 weeks)

研究者

发起方
Oliver Faude
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Oliver Faude

Prof. Dr.

University of Basel

研究点 (2)

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