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Clinical Trials/NCT05727254
NCT05727254
Completed
N/A

Agility Training for Older Adults: A Randomized Controlled Trial

Oliver Faude1 site in 1 country48 target enrollmentJuly 13, 2022

Overview

Phase
N/A
Intervention
Not specified
Conditions
Age-Related Loss of Skeletal Muscle Mass
Sponsor
Oliver Faude
Enrollment
48
Locations
1
Primary Endpoint
Isometric knee-extension strength
Status
Completed
Last Updated
last year

Overview

Brief Summary

In this randomized controlled trial the effect of 4 months of multi-component (strength, balance, cognition, endurance) exercise training intervention on measures of neuromuscular performance, cognition, and endurance as well as neural adaptations on a central and peripheral level is investigated. 40 subjects are recruited that are generally health and between 60 and 80 years of age. The interventions is based around exercises, where different tasks have to be solved simultaneously rather than serially, as has previously been done.

Registry
clinicaltrials.gov
Start Date
July 13, 2022
End Date
December 15, 2023
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor Investigator
Principal Investigator

Oliver Faude

Prof. Dr.

University of Basel

Eligibility Criteria

Inclusion Criteria

  • willing to be randomized to either arm
  • ability to travel to the sports facility twice a week
  • understanding the german language

Exclusion Criteria

  • smoking, obesity
  • history of cardiovascular, pulmonary or chronic inflammatory disease
  • vision impairments
  • orthopaedic problems preventing them from participating in an exercise program
  • history of osteoporosis or recent low trauma fracture
  • less than two weeks during the intervention period
  • not have taken part in a structured exercise program more than once a week in the past three months

Outcomes

Primary Outcomes

Isometric knee-extension strength

Time Frame: 16 weeks

Strength in torque (N\*m) of the quadriceps femoris muscle. Measured on an isokinetic device in an isometric condition.

Secondary Outcomes

  • Cognitive Processing Speed(16 weeks)
  • Balance Performance(16 weeks)
  • Isometric knee-flexion strength(16 weeks)
  • Cognitive Impulsiveness(16 weeks)
  • Pulse Wave Velocity(16 weeks)
  • Retinal vessel diameter(16 weeks)
  • Depression(16 weeks)
  • Hand Grip Strength(16 weeks)
  • Blood Pressure(16 weeks)
  • Fall Efficacy(16 weeks)
  • Sleep Disturbances(16 weeks)
  • Stress(16 weeks)
  • Counter movement jump power(16 weeks)
  • Quality of Life Questionnaire(16 weeks)

Study Sites (1)

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