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临床试验/NCT04014439
NCT04014439已完成不适用

Relationship Between Neutrophil to Lymphocyte Ratio and Prealbumin Serum Levels With Diaphragm Thickness in Critical Patients

Indonesia University1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2019年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Ratio of Neutrophil to Lymphocyte

研究概览

简要总结

A study to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.

详细描述

Weaning from ventilator sometimes can be failed and it happened due to several factors. One of the causes was Ventilator Induced Diaphragm Dysfunction (VIDD). This VIDD process occurred due to thinning process of the diaphragm thickness or decreased diaphragm muscle mass. The whole process happened due to inflammatory reaction that usually appeared on patients in Intensive Care Unit (ICU). Thus, this study was aimed to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
17 Years 至 70 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Critical patients treated in intensive care unit using mechanical ventilation from day
  • Patients are clinically predicted to be treated for more than 5 days (qSOFA and clinical assessment)

排除标准

  • History of suffering from neuromuscular disease and or diaphragmatic malformations
  • Used non-invasive ventilation before starting to use mechanical ventilation
  • History of tracheostomy
  • Patients admitted to ICU within 12 months before this study

结局指标

主要结局

Ratio of Neutrophil to Lymphocyte

时间窗: 5 days

Level of Prealbumin Serum

时间窗: 5 days

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Rudyanto Sedono

Medical Staff

Indonesia University

研究点 (1)

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