Relationship Between Neutrophil to Lymphocyte Ratio and Prealbumin Serum Levels With Diaphragm Thickness in Critical Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Inflammatory Response
- Sponsor
- Indonesia University
- Enrollment
- 30
- Locations
- 1
- Primary Endpoint
- Ratio of Neutrophil to Lymphocyte
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
A study to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.
Detailed Description
Weaning from ventilator sometimes can be failed and it happened due to several factors. One of the causes was Ventilator Induced Diaphragm Dysfunction (VIDD). This VIDD process occurred due to thinning process of the diaphragm thickness or decreased diaphragm muscle mass. The whole process happened due to inflammatory reaction that usually appeared on patients in Intensive Care Unit (ICU). Thus, this study was aimed to find the relationship between neutrophil to lymphocyte ratio (NLR) with diaphragm thickness of critical patients in ICU.
Investigators
Rudyanto Sedono
Medical Staff
Indonesia University
Eligibility Criteria
Inclusion Criteria
- •Critical patients treated in intensive care unit using mechanical ventilation from day
- •Patients are clinically predicted to be treated for more than 5 days (qSOFA and clinical assessment)
Exclusion Criteria
- •History of suffering from neuromuscular disease and or diaphragmatic malformations
- •Used non-invasive ventilation before starting to use mechanical ventilation
- •History of tracheostomy
- •Patients admitted to ICU within 12 months before this study
Outcomes
Primary Outcomes
Ratio of Neutrophil to Lymphocyte
Time Frame: 5 days
Level of Prealbumin Serum
Time Frame: 5 days