Menopausal Treatment Using Relaxation Exercises (MaTURE)
- Conditions
- Hot FlushesHot Flashes
- Registration Number
- NCT01466998
- Lead Sponsor
- University of California, San Francisco
- Brief Summary
Hot flashes occur in as many as two thirds of U.S. women during menopause and are severe enough to require treatment in 20%. Although postmenopausal hormone therapy is effective in suppressing hot flashes, it is associated with increased risk for a variety of serious adverse effects. There is an urgent need for alternative treatments that are effective, safe, and easy to use. In this study, the investigators will compare two different types of behavioral relaxation therapies, paced respiration and music therapy, for treatment of menopausal hot flashes. Effects on frequency of hot flashes, other symptom and quality-of-life outcomes associated with hot flashes, and physiologic measures of sympathetic/parasympathetic activity will be examined.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 123
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Change in average daily frequency of hot flashes. 4-Weeks and 12-Weeks
- Secondary Outcome Measures
Name Time Method Change in subjective severity of hot flashes. 4-weeks and 12-weeks Change in sympathetic and parasympathetic autonomic nervous system tone. 12 weeks Change in quality-of-of life measures associated with hot flashes. Weeks 4 and Weeks 12
Trial Locations
- Locations (1)
University of California, San Francisco
🇺🇸San Francisco, California, United States
University of California, San Francisco🇺🇸San Francisco, California, United States