跳至主要内容
临床试验/NCT01466998
NCT01466998已完成不适用

Menopausal Treatment Using Relaxation Exercises (MaTURE)

University of California, San Francisco2 个研究点 分布在 1 个国家目标入组 123 人开始时间: 2012年1月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
123
试验地点
2
主要终点
Change in average daily frequency of hot flashes.

研究概览

简要总结

Hot flashes occur in as many as two thirds of U.S. women during menopause and are severe enough to require treatment in 20%. Although postmenopausal hormone therapy is effective in suppressing hot flashes, it is associated with increased risk for a variety of serious adverse effects. There is an urgent need for alternative treatments that are effective, safe, and easy to use. In this study, the investigators will compare two different types of behavioral relaxation therapies, paced respiration and music therapy, for treatment of menopausal hot flashes. Effects on frequency of hot flashes, other symptom and quality-of-life outcomes associated with hot flashes, and physiologic measures of sympathetic/parasympathetic activity will be examined.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
40 Years 至 59 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • 未提供

排除标准

  • 未提供

结局指标

主要结局

Change in average daily frequency of hot flashes.

时间窗: 4-Weeks and 12-Weeks

次要结局

  • Change in subjective severity of hot flashes.(4-weeks and 12-weeks)
  • Change in sympathetic and parasympathetic autonomic nervous system tone.(12 weeks)
  • Change in quality-of-of life measures associated with hot flashes.(Weeks 4 and Weeks 12)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Deborah Grady

Professor of Medicine

University of California, San Francisco

研究点 (2)

Loading locations...

相似试验