The Use of Tranexamic Acid (TXA) Intravenously, to Reduce Blood Loss in Proximal Femur Surgery
试验速览
- 阶段
- 4 期
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Evaluation of blood loss in ml.
研究概览
简要总结
The use of Tranexamic Acid (TXA) intravenously, to Reduce Blood Loss in proximal femur surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 60 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients over 60, who came to the orthopedic department for proximal femur fracture surgery
- •Sound judgment
排除标准
- •Known hypersensitivity to Tranexamic Acid or component solution provided
- •Subarachnoid hemorrhage
- •Acquired color blindness
- •Myocardial infarction in 12 months before admission
- •Unstable angina
- •Known clotting disorders (Thromboembolic disease in the past, elongated PT and PTT, hypercoagulability),
- •Kidney or liver failure
- •Another situation prostate resection , pathologic fractures according to anamnesis or by imaging
- •Oncology patients
- •Patients on anticoagulation
- •Patients undergoing vascular intervention ( coronary or peripheral ), which was inserted Supporter requires a Dual antiplatelet therapy
研究组 & 干预措施
Tranexamic Acid (TXA) treatment
Tranexamic Acid (TXA) treatment
干预措施: Tranexamic Acid (TXA) treatment (Drug)
结局指标
主要结局
Evaluation of blood loss in ml.
时间窗: up to 13 months
Hbloss=BV X (Hbi - Hbe) X 0.001 + Hbt Hbi - hemoglobin level before the surgery ) gram X liter-1(. Hbe - hemoglobin level 3 days after the surgery ( gram X liter-1). Hbt - The amount of hemoglobin that was given in the blood transfusion (gram). Hbloss - Change of hemoglobin loss. After calculating the amount of loss of hemoglobin, the volume of blood lost can be found: Blood loss = 1000 X Hbloss/ Hbi Evaluation of blood loss will be through: 1. Comparing hemoglobin level before and after surgery and calculation of quantitative Change of hemoglobin loss. 2 .Registration evaluating blood loss at the end of surgery 3. Collecting and recording blood drain. 4. Tracking Blood Transfusion. Of course we collect the data: assessment of bleeding in the analysis, the number of blood units given, the amount of blood collected drain
次要结局
未报告次要终点