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A New Micro Swim-up Procedure for Sperm Preparation in ICSI Treatment

Conditions
Microswimup Procedure Efficacy
Registration Number
NCT02672124
Lead Sponsor
Cervesi Hospital, Cattolica, Italy
Brief Summary

The aim of this study is to evaluate the microbiological safety and the efficacy of a new not expensive, easy and fast technique (Direct Microswimup) for sperm preparation in In Vitro Fertilization (IVF) treatments without the use of centrifuge, able to simplify the procedure and to avoid mismatches by ensuring the same results of the standard techniques in terms of fertilization rate, blastulation rate, pregnancy/abortion rate, cryostorage rate, and a better euploid status of the embryos.

Detailed Description

Not available

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
100
Inclusion Criteria
  • at least 8 oocytes retrieved at pickup
  • oocyte insemination with ICSI technique
  • only elective single embryo transfer (eSET) at blastocyst stage
  • sperm concentration ≥ 1 X 106 /ml
  • absence of antibiotic treatment in the previous four weeks for male patients
Exclusion Criteria
  • recurrent miscarriages
  • more than three in vitro fertilization treatment
  • azoospermia

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
microbiological test3 months

A standard bacteriological culture \[based on inoculation of blood and "chocolate" agar plates and Brain-Heart Infusion broth, followed by incubation at 37°C for up to 72 hours\] was performed in order to investigate the presence and amount of colonizing bacteria delivered with the semen at ejaculation and after treatment

Secondary Outcome Measures
NameTimeMethod
semen treatment efficacy6 months

number of obtain blastocysts (%) and number of pregnancy (%)

Trial Locations

Locations (2)

Cervesi Hospital IVF Unit

🇮🇹

Cattolica, Rimini, Italy

Primiterra Mariangela

🇮🇹

Cattolica, Rimini, Italy

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