Molecular Characterization of Gliomas Using a Broad NGS Panel
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 32
- 主要终点
- The prevalence of genetic alterations in patients with high grade glioma using a 80 gene NGS panel
研究概览
简要总结
Gliomas are the most common malignant primary brain tumors with poor prognosis. The genotyping of tumors using NGS platforms enables the identification of genetic alterations that constitute diagnostic, prognostic and predictive biomarkers.Here in, we investigated the molecular profile of 32 tumor samples from 32 patients with high grade gliomas by implementing a broad 80-gene targeted NGS panel while reporting their clinicopathological characteristics and outcomes.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Diagnosis of high grade glioma based on tissue biopsy
排除标准
- 未提供
结局指标
主要结局
The prevalence of genetic alterations in patients with high grade glioma using a 80 gene NGS panel
时间窗: April 2019 - December 2021
The prevalence of genetic alterations in patients with high grade glioma using a 80 gene NGS panel
次要结局
未报告次要终点
研究者
Rania Romanidou
Dr Ourania Romanidou
Hellenic Cooperative Oncology Group