Effects of Different Polyphenol-containing Beverages on the Immune System and on Muscular Growth Factors
Not Applicable
Completed
- Conditions
- Food Sensitivity
- Registration Number
- NCT04983420
- Lead Sponsor
- Balgrist University Hospital
- Brief Summary
In this research project, the effect of different polyphenol-containing beverages with varying alcohol content of \< 0.4 vol% on immune function as well as muscular growth factors will be investigated
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
- Healthy
- Age 20 - 60 years
- Written informed consent
Exclusion Criteria
- severe gastrointestinal disease or known malabsorption
- use of proton pump inhibitors
- malignancies
- rheumatoid diseases
- metabolic syndrome
- acute or chronic infections or inflammatory diseases
- use of medications or supplements to interfere with immune function
- alcohol and/or drug abuse or addiction
- dependent relationship with the project manager or his or her employees
- pregnancy or breastfeeding
- chronic illness or regular use of medication (except hormonal contraception)
- smoker
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Primary Outcome Measures
Name Time Method white blood cells after 14 days of daily intake white blood cell count
inflammatory markers in the blood after 14 days of daily intake IL-6, TNF- α, hs-CRP
polyphenol in the urine after 14 days of daily intake polyphenol level in the urine
blood alcohol after 14 days of daily intake blood alcohol level
- Secondary Outcome Measures
Name Time Method physical activity day 14 of beverage intake Global Physical Activity Questionnaire (allows to calculate metabolic equivalents to express the intensity of physical activities
dietary habit day 12-14 of beverage intake 3 day food diary
Trial Locations
- Locations (1)
Balgrist University Hospital
🇨🇭Zurich, Switzerland
Balgrist University Hospital🇨🇭Zurich, Switzerland