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Immunogenicity and safety of SARS-CoV-2 (COVID-19 virus) vaccine in liver transplant recipients

Completed
Conditions
Immunogenicity and safety of SARS-CoV-2 vaccine in liver transplant recipients
liver transplant, vaccine, COVID-19, SARS-CoV-2, safety
Registration Number
TCTR20210526004
Lead Sponsor
Faculty of medicine, Chulalongkorn university
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
60
Inclusion Criteria

Liver transplant recipients who fulfil
1. Liver transplantation more than 3 months
2. No acute cellular rejection within 1 month

Exclusion Criteria

1. History of SARS-CoV-2 infection
2. Pregnancy or lactation
3. Anaphylaxis to COVID-19 vaccine

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Immunogenicity of vaccine 1 and 3 months after primary vaccination & 1 month after booster dose Neutralizing antibody and t-cell specific response
Secondary Outcome Measures
NameTimeMethod
Safety of vaccine 1 and 3 months after primary vaccination & 1 month after booster dose Patient reported adverse events
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