KCT0004859
Completed
未知
A prospective study for connective tissue disease related digital ulcer in Korea
Soon Chun Hyang University Hospital Seoul0 sites35 target enrollmentTBD
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Diseases of the musculo-skeletal system and connective tissue
- Sponsor
- Soon Chun Hyang University Hospital Seoul
- Enrollment
- 35
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •adult patients with systemic slerosis(SSc) or mixed connective tissue disease(MCTD) with active digital ulcers, with or without pulmonary arterial hypertension (PAH), in the last 6 months, from the rheumatology department of the 4 institutions
- •All patients fulfilled the 2013 American College of Rheumatology/EULAR classification criteria or the MCTD criteria according to Sharp et al.
Exclusion Criteria
- •Patients were excluded if they had taken phosphodiesterase type 5 (PDE\-5\) inhibitors or other endothelin receptor antagonists within 1 month and had used prostacyclin analogues within the previous 3 months 4\. The concurrent use of aspirin, calcium channel blocker (CCB), angiotensin\-converting enzyme inhibitor (ACEi), and angiotensin II receptor blocker (ARB) was acceptable at the same dose as the last 4 weeks before study enrollment.
Outcomes
Primary Outcomes
Not specified
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