Effect of Tiaojing Cuyun acupuncture on hypothalamic functional connectivity in patients with primary ovarian insufficiency based on multimodal functional magnetic resonance imaging

Jiangsu Provincial Traditional Chinese Medicine Hospital0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•The study will enroll patients with a diagnosis of POI who meets the following inclusion criteria:
•(1) patients meeting the ESHRE Guideline diagnostic criteria for POI, right-handed;
•(2) women between the ages of 18 and 40 years;
•(3) and no acupuncture therapy within 2 months prior to study recruitment;
•(4) sign the informed consent form and willing to participate in the study;
•Patients meeting the following criteria will be selected as study volunteers:
•(1) right-handed women between the ages of 18 and 40, age matched with POI patients;
•(2) good health, no genetic history of familial psychosis, no claustrophobia;
•(3) no metal substances in the body that affect functional magnetic resonance examination;
•(4) not in pregnancy, postpartum lactation;
•(5) sign the informed consent form and volunteer to participate in the study.

•Patients meeting any of the following criteria will be excluded from the study:
•1. abnormal development of congenital reproductive organs, or uterus, bilateral ovarian or bilateral salpingectomy, combined with severe primary diseases such as cardiovascular, renal, hepatic and hematopoietic systems;
•2. endocrine diseases such as polycystic ovary syndrome, hyperprolactinemia, hyperandrogenism, hypothyroidism, and chronic adrenal insufficiency affect ovulation;
•3. install a pacemaker, metal allergy or severe fear of the needle, claustrophobia;
•4. mental or behavioral disorders that do not match the completion of clinical observations;
•5. patients who are likely to be lost to follow-up according to the judgment of the investigator, such as patients whose work environment changes frequently, whose living environment is unstable;
•6. who are participating in other drug clinical trials.

发起方

Jiangsu Provincial Traditional Chinese Medicine Hospital