Atrial mechanics as predictors of atrial fibrillation’s recurrence after pulmonary vein isolation - EchoAM-AF

niveristy Hospital Centre Sisters of Charity0 个研究点目标入组 150 人开始时间: 2016年5月10日最近更新: 2024年8月19日

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•Men and women, 18-85 years of age with paroxysmal and persistent atrial fibrillation who will undergo pulmonary vein isolation and who are able to understand and sign an informed consent will be included in the study. Paroxysmal atrial fibrillation is defined as atrial fibrillation with self-terminating episodes lasting up to a maximum of 7 days, while persistent atrial fibrillation is defined as atrial fibrillation lasting more than 7 days and/or that required the use of cardioversion (either with antiarrhytmic drugs or electrocardioversion)in ending the episode. Both definitions are taken from the international guidelines of the European Society for Arrhythmias (EHRA) which is part of the European Society of Cardiology (ESC).

•1. Patients on whom the pulmonary vein isolation was already done (re-do PVIs)
•2. Patients with < 40% left ventricular ejection fraction
•3. Patients with persistent atrial fibrillation lasting longer > 12 months (long lasting atrial fibrillation) or permanent atrial fibrillation
•4. Patients with contraindication for using anticoagulant therapy
•5. Patients with intracavitary clot which is contraindication for pulmonary vein isolation
•6. Patients on whom cavotricuspid isthmus ablation was done
•7. Patients on whom echocardiography was not done or it was of low quality
•8. Patients who are not in sinus rhythm at the time of performing echocardiography
•9. Patients with implanted permanent pacemaker or cardioverter-defibrilator or CRT
•10. Patients who underwent cardiothoracic surgery (myocardial revascularisation and/or valvular reparation or replacement)
•11. Patients with congenital heart disease (surgically corrected or not)
•12. Patients with one or more moderate or heavy valvular disease
•13. Pregnant women
•14. Patients with hyperthyreosis
•15. Chronic obstructive pulmonary disease (COPD)
•16. Patients with a history of pulmonary embolism
•17. Patients with expected life expectancy < 12 months
•18. Patients with anaemia (haemoglobin <100 g/L)
•19. Patients with history of alcohol or drug abuse
•20. Patients included in other clinical study
•21. Patients with the present state of emergency during hospitalization and not caused by heart disease

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niveristy Hospital Centre Sisters of Charity