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临床试验/NCT01139099
NCT01139099已完成不适用

Department of Psychiatry of NTUH Yun-Lin Branch

National Taiwan University Hospital2 个研究点 分布在 1 个国家目标入组 50 人开始时间: 2010年5月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
50
试验地点
2
主要终点
re-hospitalization rate

研究概览

简要总结

Although the patients with schizophrenia can be treated with new generation of antipsychotics medication, additional approaches are necessary to improve schizophrenics' cognitive functions, interpersonal relationships as well as social adjustment. When some of patients return to community, they expose to practical pressure that contribute to worsen and relapse of disease. That further damages patient's cognitive functions. Integrated Psychological Therapy(IPT) on treating schizophrenia has dramatic improvement in recent years; it has formed structured treatment gradually on relieving illusion, hallucination as well as negative symptoms. This study aims at conducting 12-week structured IPT group therapy. The intended subjects are patients, met with DSM-Ⅳ-TR diagnosis of schizophrenia, from community, outpatient and inpatient service. The overall treatments are designed to provide 1-2 hours weekly group therapy which focuses on relieving illusions, hallucination, and negative symptoms. Patients' cognitive functions, ability of emotional adjustment and interpersonal relationship would be evaluated in pre-test and post-test to indicate whether the significant difference exists. There is a controlled group, in which patients who still receive treatment as usual (TAU). The study also compares the evaluation results between IPT group and TAU group, hoping to develop the therapeutic framework for Taiwan people with schizophrenia.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • schizophrenia,
  • can concentrate in group for 30 minutes.

排除标准

  • substance abuse (alcohol, illegal medication),
  • self harm history.

结局指标

主要结局

re-hospitalization rate

时间窗: after 3 months of the group psychotherapy

acute symptom relapse and needed to be admitted to the acute ward

次要结局

  • Cognitive functions, ability of emotional adjustment, and interpersonal relationship(12 months of the group tpsychotherapy)
  • The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test(12 months of the group psychotherapy)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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