Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions

Not Applicable

Completed

• Conditions: Attachment Loss, Periodontal; Gingival Recession, Localized; Sensitivity, Tooth
• Interventions: Procedure: Coronally advanced flap with connective tissue graft

• Registration Number: NCT05923294
• Lead Sponsor: Kutahya Health Sciences University

Brief Summary

The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in localized recessions of anterior and premolar teeth. In addition, it is aimed to compare the postoperative gingival thickness between the two techniques. The secondary aim is to search the effects of both techniques on periodontal parameters and to evaluate patient-centered outcomes.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2023-06-20
• Study First Submitted QC: 2023-06-20
• Study First Posted: 2023-06-28
• Status Verified: 2023-07
• Study Start: 2023-08-10
• Primary Completion: 2024-03-01
• Study Completion: 2024-07-03
• Last Update Submitted: 2024-08-12
• Last Update Posted: 2024-08-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

1. American Society of Anesthesiologists physical status class 1 and 2 patients,healthy patients
2. Nonsmokers
3. Periodontally healthy patients
4. Localized gingival recessions (Miller I, II, and Cairo I recessions with a depth of recession of at least 2 mm) in anterior and premolar teeth

Exclusion Criteria

1. Medically compromised patients, especially uncontrolled diabetes
2. Pregnancy, lactation, or suspicion of pregnancy,
3. Poor oral hygiene
4. Recessions associated with caries or restoration

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
De-epithelialized free gingival graft	Coronally advanced flap with connective tissue graft	In this split-mouth randomized controlled trial, the coin toss method will determine test and control groups. In both groups, connective tissue graft with a trapezoidal flap design will be applied to the recession area. To obtain the connective tissue graft, the traditional free gingival graft will be de-epithelialized in the control group.
De-epithelialized gingival unit graft	Coronally advanced flap with connective tissue graft	In this split-mouth randomized controlled trial, the coin toss method will determine test and control groups. In both groups, connective tissue graft with a trapezoidal flap design will be applied to the recession area. To obtain the connective tissue graft, the gingival unit graft will be de-epithelialized in the test group.

Primary Outcome Measures

Name	Time	Method
Root coverage percentage	Postoperative 6th month	The comparison of the postoperative recession depth to the initial recession depth
Gingival thickness	Preoperative and postoperative 6th month	Gingival thickness in the mid-buccal of the recession defect measured with an endodontic spreader and digital recordings

Secondary Outcome Measures

Name	Time	Method
Vestibular depth	Preoperative and postoperative 6th month	The distance from the gingival margin to the greatest concavity of the mucosal fold
Recession width	Preoperative and postoperative 6th month	Recession width measured at the cemento-enamel junction
Keratinized gingiva width	Preoperative and postoperative 6th month	Mid-buccal gingival width measured with a periodontal probe
Probing depth	Preoperative and postoperative 6th month	Probing depth measured at the mid-buccal of the recession defect
Pain perception	Postoperative 1st week	Visual analog scale where higher scores mean a worse outcome and has a minimum value of 0 and a maximum value of 10
Clinical attachment loss	Preoperative and postoperative 6th month	Clinical attachment loss measured at the mid-buccal of the recession defect
Bleeding related to the procedure	Postoperative 1st week	Bleeding evaluated by a dichotomous index

Trial Locations

Locations (1)

Kutahya Health Sciences University; 🇹🇷 Kutahya, Turkey