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Clinical Trials/NCT05700747
NCT05700747
Completed
Not Applicable

Health Through Activity: A Pilot Study of a Rehabilitation Intervention for People Living With Multiple Myeloma

MGH Institute of Health Professions1 site in 1 country5 target enrollmentFebruary 1, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Multiple Myeloma
Sponsor
MGH Institute of Health Professions
Enrollment
5
Locations
1
Primary Endpoint
Rate of Participant Enrollment
Status
Completed
Last Updated
4 months ago

Overview

Brief Summary

The purpose of this study is to explore whether a structured program can help reduce the challenges of decreased physical functioning and quality of life for participants with multiple myeloma by providing a customized exercise program and fostering engagement in meaningful activities.

The name of the study intervention involved in this study is:

Health Through Activity (HTA) (six-session, rehabilitation exercise regimen)

Detailed Description

The goal of this single arm, pilot study of the Health Through Activity (HTA) rehabilitation intervention for people living with multiple myeloma is to determine if investigators can feasibly deliver the program out of the IMPACT Practice Center at the MGH Institute for Health Professions. \- The six-session 'Health Through Activity' program provides a customized exercise plan and encourages engagement in activities to reduce disability and improve quality of life. * Study procedures including screening for eligibility, in-clinic visits, questionnaires, and surveys. * Participation in this research study is expected to last up to 4 months. It is expected that up to 20 people will take part in this research study. An internal grant from the Massachusetts General Hospital Institute of Health Professions is providing equipment and staffing for this study.

Registry
clinicaltrials.gov
Start Date
February 1, 2023
End Date
March 28, 2025
Last Updated
4 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Sponsor
MGH Institute of Health Professions
Responsible Party
Principal Investigator
Principal Investigator

Kathleen Lyons, ScD, OTR/L

Principal Investigator

MGH Institute of Health Professions

Eligibility Criteria

Inclusion Criteria

  • ≥18 years of age
  • Diagnosed with multiple myeloma currently receiving maintenance therapy,
  • Experiencing disability as indicated by an answer of "yes" to the question "Do health problems interfere with your ability to carry out your social or day to day activities?"

Exclusion Criteria

  • Bone pain that is either a) new onset or increased in the past month or b) uncontrolled i.e., in the patient's estimation the bone pain "greatly interferes with daily activities"
  • History of fracture in the past 12 months without fixation, or
  • Any injury or medical condition that would prohibit being able to safely perform exercise as indicated by the Physical Activity Readiness Questionnaire\[29\] (i.e., atrial fibrillation, chest pain or angina, uncontrolled high blood pressure or hypertension, loss of balance due to dizziness in the past 12 months, or loss of consciousness in the past 12 months).
  • We will also exclude individuals with moderate or worse cognitive impairment as indicated by a score of 3 or less on the Callahan six item cognitive screening tool.

Outcomes

Primary Outcomes

Rate of Participant Enrollment

Time Frame: At screening

Number participants enrolled / Number screened positive \& eligible. A rate of at least 75% will indicate feasibility.

Assessment Completion Rate

Time Frame: Up to 4 months

Defined as the number of participants completing each of the three study assessments to number of participants enrolled. A completion rate of 85% will indicate feasibility.

Eligibility Rate

Time Frame: Up to 4 months

Number patients screening positive \& eligible / Number screened. Eligibility rate is influenced by how many people in the clinical population are experiencing disability. Based on our pilot study, expected rate to be at least 35%.

Screening Rate

Time Frame: Up to 4 months

Number patients screened/ Number patients identified as potentially eligible. Screening rate of at least 75% will indicate feasibility

Secondary Outcomes

  • Intervention Completion Rate(Up to 3 months)
  • Participant Satisfaction(Up to 4 months)

Study Sites (1)

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