Comparing individualized homoeopathy with placebo in managing pain of knee osteoarthritis: a double blind randomized controlled trial - OA-RCT

Central Council for Research in Homoeopathy0 个研究点目标入组 200 人开始时间: 待定最近更新: 2021年11月24日

试验速览

暂无简介。

•Patients above the age of 50 years, presenting with knee pain and evidence of osteophytes in the knee radiograph

•Rheumatoid factor more than 1:40 titre
•ESR more than 40mm/hour
•Serum uric acid level >7 mg/dL in men or >6 mg/dL in women
•Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee ( > 12Â°); evidenced by imaging or other evidences and requiring surgical intervention
•Non-ambulant patients
•Self-reported joint disorders (e.g. inflammatory joint disease, specific arthropathy, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs) other than OA
•IA injections within 2 weeks prior to study entry
•Cases with other systemic unevaluated or uncontrolled diseases like diabetes mellitus, hypertension, or other cardiovascular, renal, gastro-intestinal, endocrinal, gynecological diseases etc. or systemic infections affecting quality of life or on other treatment therapies
•Psychiatric illness
•Patients with any vital organ failure
•Recent knee surgery within last 6 months
•Cases with transplanted knees
•History of homeopathic treatment for any chronic disease within last 6 months
•Self-reported immune-compromised states
•Alcohol and/or drug addiction or dependence
•Cases with controlled/uncomplicated hypertension, diabetes mellitus, etc. will not be excluded. Patients on life-saving conventional drug therapies, e.g. anti-diabetics, anti-hypertensives, thyroid drugs etc. for co-morbidities under control, will be continued.

发起方

Central Council for Research in Homoeopathy