Eye-movement Recordings in the Diagnosis of Traumatic Brain Injury
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Traumatic Brain Injury
- Sponsor
- VA Office of Research and Development
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- Stability of Fixation
- Status
- Completed
- Last Updated
- 10 years ago
Overview
Brief Summary
The study investigates whether the use of eye movement recordings can provide a reliable diagnostic of previously undiagnosed mild traumatic brain injury (blast and impact) in Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans.
Detailed Description
Eye movements are recorded for Operations Enduring Freedom or Iraqi Freedom (OIF/OEF) veterans with mild traumatic brain injury (mTBI) and compared to the eye movements of those without mTBI. By analyzing and characterizing the differences between the two groups, a diagnostic measure of mTBI through the use of eye movements can be developed.
Investigators
Eligibility Criteria
Inclusion Criteria
- •OIF/OEF Veteran;
- •Neuropsych diagnosis of MTBI
Exclusion Criteria
- •chronically abusing alcohol or illicit drugs.
- •uncorrected vision prevents subject from effectively viewing the stimuli, unless they can wear contact lenses during the recording session.
- •inability to make normal eye movements (i.e.: saccades, smooth pursuit) required by study paradigms. Note: Deficit can be caused by taking medications that can potentially affect eye movements or any neurological condition that can interfere with making normal eye movement.
- •psychological or psychiatric conditions that preclude sustained concentration or ability to perform the tasks.
Outcomes
Primary Outcomes
Stability of Fixation
Time Frame: During eye movement recording session (20 sec).
The ability to keep eye position fixed on a visual target, measured by the distance between the target and eye fixation point averaged over 20 sec.