Screening For Critical Congenital Anomalies In NICU And Their Out Come in Assiut Universty
试验速览
- 阶段
- 不适用
- 入组人数
- 142
- 主要终点
- detect number of total babies and percentages of congenital anomalies
研究概览
简要总结
The congenital malformation (CMF) include disturbance in normal process of organogenesis occurring before birth .
- The (CMF) are structural ,functional, or (biochemical Molecular) defect presenting at birth.
- The structural defect resulting from prenatal insult during period of embryogeneses.
- The neonate with congenital malformation have differences in physiology, anatomy, in response to stress.
- The (CMF) are important causes of infant disability , illness, deaths.
- (CMF) classified into mild, moderate, severe and lethal
详细描述
The (CMF) may be structural abnormalities with significant effect on function (e.g) cleft palate .
Or minimal effect on clinical function but may have cosmotic impact (e.g) pre-auricular pit .
In developed countries, outcome of neonatal congenital anomalies is favourable because of availability of antenatal diagnosis, improved surgical skills and technologies, sophisticated neonatal intensive care unit, availability of total parenteral nutrition and adequate staff.
In developing countries, however, neonatal surgery is still fraught with a lot of problems including late presentation and lack of medical facilities and human resources, thereby, making newborn surgery to be associated with unacceptably high morbidity and mortality.
Due to the burden of other neonatal and childhood diseases in developing countries, neonatal surgery is often considered low priority in healthcare budget planning and allocation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Day 至 6 Months(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •• Cases need resustation and stabilization.
- •Congenital anomalies that need admission in NICU eg: impeforated anus , meningiocele, heart disease, tacho osphageal fistula, urinary problems, diaphragmatic hernia, intestinal obstruction, duedodnal obstruction, neural tube defect .
排除标准
- •All vitally stable cases that don't need NICU admission and all cases not need immediate intervention of congenital anomalies
结局指标
主要结局
detect number of total babies and percentages of congenital anomalies
时间窗: 24 hours
次要结局
未报告次要终点
研究者
Amira Tharwat Helmy
principal investigator
Assiut University
