跳至主要内容
临床试验/NCT07736469
NCT07736469尚未招募不适用

Multimodal Decision Support for Perioperative Risk Stratification in Older Adults Undergoing Surgery for Fracture

Shanghai Jiao Tong University Affiliated Sixth People's Hospital0 个研究点目标入组 4,000 人开始时间: 2026年10月8日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
4,000
主要终点
All-cause mortality within 365 days after fracture surgery

研究概览

简要总结

The goal of this observational study is to establish a standardized multicenter cohort and develop and validate clinically interpretable models for perioperative risk stratification, brain-state risk prediction, objective pain assessment, sleep-pain-delirium association analysis, and longer-term prognosis.The main questions it aims to answer are:

Can clinically interpretable predictive models be developed for perioperative risk stratification and brain-state changes? What are the associations among objective pain measures, sleep quality, and postoperative delirium? Are these perioperative factors associated with longer-term patient outcomes? This is a multicenter cohort study without a separate comparator group. Participants will undergo routine perioperative clinical assessments and standardized follow-up evaluations according to the study protocol.

详细描述

Approximately 4,000-4,500 participants: 2,800-3,000 retrospective records and 1,200-1,500 prospectively enrolled participants

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Other

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who have hip fracture or another eligible fracture requiring perioperative management and who undergo, or are scheduled to undergo, fracture surgery

排除标准

  • 未提供

结局指标

主要结局

All-cause mortality within 365 days after fracture surgery

时间窗: 365 days after fracture surgery

次要结局

未报告次要终点

研究者

发起方
Shanghai Jiao Tong University Affiliated Sixth People's Hospital
申办方类型
Other
责任方
Principal Investigator
主要研究者

Hui Zhang

Chief Physician, Department of Anesthesiology

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

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