Effect of Low-carbohydrate/High-fat Diet on Glucose Tolerance and Lipid Profile in Lean, Healthy Women
Not Applicable
Completed
- Conditions
- Insulin SensitivityWeight
- Interventions
- Other: LCHF diet and a bout of exercise
- Registration Number
- NCT02005224
- Lead Sponsor
- Atlantis Medical University College
- Brief Summary
Intervention studying the effect of a low-carbohydrate/high-fat (LCHF) diet as well as on bout of exercise in combination with either a normal diet or a LCHF diet, in relation to glucose metabolism, insulin sensitivity, lipid profile and body composition.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 17
Inclusion Criteria
- Females
- Normal weight
- BMI between 18.5 and 25
- Moderately trained
Exclusion Criteria
- Smokers/tobacco users
- pregnancy
- familial cardio-vascular-disease
- diabetes or reduced glucose tolerance
- under- or overweight (BMI under 18.5 or over 25)
- top athletes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description LCHF diet and a bout of exercise LCHF diet and a bout of exercise LCHF diet for 3 weeks, where E% 70 fat, E% 20-25 proteins and 20g or less carbohydrates. Oral glucose tolerance test on the morning of day 21 followed by a bout of exercise in the afternoon (indoor bicycle, 60min at 75% HFpeak). The following morning (day 22) a new oral glucose tolerance test. Oral glucose tolerance test results from pre-tests used to determine the effect of LCHF and a bout of exercise on insulin sensitivity.
- Primary Outcome Measures
Name Time Method Area under the curve glucose (0, 15, 30, 45, 60, 90 and 120 min) -1 week, 3 weeks performed by oral glucose tolerance test, 75 g glucose, 300 ml water
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Norwegian School of Sport Sciences
🇳🇴Oslo, Norway