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Clinical Trials/NCT06809985
NCT06809985CompletedNot Applicable

Latent Phase Membrane Stripping for Caesarean Section Reduction. Single Blind Clinical Trial

Ricardo A Gutierrez Ramirez, MD, MSc, FACOG1 site in 1 country71 target enrollmentStarted: January 31, 2025Last updated:
Conditions
Interventions

Trial Snapshot

Phase
Not Applicable
Status
Completed
Sponsor
Enrollment
71
Locations
1
Primary Endpoint
Time from admission until active phase

Study Overview

Brief Summary

In the Hospital Escuela, the availability of beds and criteria for admission to the intensive care unit ICU are not the same, the use of this marker is questionable, as it is affected by the level of complexity of care provided to a health setting and the organization of obstetric care. The cesarean section rate (almost 63.2%), is without significant variation by different criteria.

The importance of finding strategies to reduce the rate of cesarean births and thus counteract the high rates of maternal morbidity and mortality is proposed. For this reason, this research is aimed at reducing the latent phase of labor through the use of the Hamilton maneuver.

Detailed Description

There is a need to find non-pharmacological interventions that can speed up delivery to prevent maternal complications and reduce the number of caesarean sections.

Maternal mortality remains one of the biggest health problems worldwide. Every day, around 830 women die worldwide from complications related to pregnancy or childbirth. In 2015, an estimated 303,000 women died during pregnancy and childbirth or after. Most of these deaths occur in low-income countries and most of them could have been prevented. The maternal mortality rate in Latin American and Caribbean countries, calculated by the Inter-Agency Group (MMEIG), shows a significant decrease as a regional average in recent years, from 88 per 100,000 live births in 2005 to 67 per 100,000 live births in 2015.

At the Escuela Hospital, the availability of beds and admission criteria in the intensive care unit (ICU) are not the same. The use of this marker is questionable, since it is affected by the level of complexity of the care provided to a health setting and the organization of obstetric care. We found in our study a cesarean section rate (almost 63.2%), with no significant variation by different criteria. This finding is consistent with that reported by Nelissen et al. Due to the severity of the obstetric conditions of these patients, their pregnancy usually requires urgent action. Although cesarean section is associated with high rates of maternal morbidity and mortality compared to vaginal delivery, when clinically indicated, timely termination of pregnancy can reduce the risk of maternal-fetal death.

Based on the above, this research proposes the importance of finding strategies to reduce the rate of cesarean deliveries and thus counteract the high rates of maternal morbidity and mortality. For this reason, this research is aimed at reducing the latent phase of labor through the use of the Hamilton maneuver.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Prevention
Masking
Single (Outcomes Assessor)

Masking Description

Both the patient and the principal investigator will know the intervention, the data analyst researcher does not know the group to which the patients have been assigned.

Eligibility Criteria

Ages
18 Years to 45 Years (Adult)
Sex
Female
Accepts Healthy Volunteers
Yes

Inclusion Criteria

  • •Submission of a signed and dated informed consent form.
  • •Declared willingness to comply with all study procedures and availability for the duration of the study.
  • •nulliparous
  • •woman with singleton pregnancy at 37 weeks or more
  • •integral membranes
  • •cephalic presentation
  • •Bishop's score less than 7
  • •No contraindication for vaginal delivery

Exclusion Criteria

  • •Previous uterine surgery
  • •Maternal condition preventing vaginal delivery
  • •Fetal anomaly
  • •Premature rupture of membranes
  • •Multiple pregnancy
  • •Fetal orbit
  • •Maternal comorbidities such as chronic arterial hypertension, type 1, 2 and gestational diabetes, hypothyroidism, among others.

Arms & Interventions

Hamilton maneuver

Experimental

The Hamilton maneuver is performed by inserting one or two fingers through the internal cervical os and carefully producing a circumferential rotational movement through the uterine segment in order to separate the fetal membranes from the decidua. This maneuver is recommended in order to reduce the need for formal induction.

Intervention: Hamilton maneuver (Procedure)

Control

No Intervention

A normal gynecological evaluation will be performed, no additional maneuvers will be performed in addition to the routine evaluation of the patient.

Outcomes

Primary Outcomes

Time from admission until active phase

Time Frame: Since intervention until 20 hours

time from the intervention to reach a cervical dilatation greater than or equal to 5 cm

Secondary Outcomes

  • Rate of cesarean births(Since intervention until 7 days or maternal discharge)
  • Level of Maternal satisfaction(Since intervention until 24 hours of delivery or maternal discharge)
  • Rate of maternal complications(Since intervention until 14 days)

Investigators

Sponsor
Ricardo A Gutierrez Ramirez, MD, MSc, FACOG
Sponsor Class
Other
Responsible Party
Sponsor Investigator
Principal Investigator

Ricardo A Gutierrez Ramirez, MD, MSc, FACOG

Titular professor

Universidad Nacional Autonoma de Honduras

Study Sites (1)

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