DRKS00025757
Completed
Phase 2
Pilot Study fostering language skills of patients with primary progressive aphasia (PPA) using a combination of speech training and brain stimulation - SPEAK
niversitätsklinikum Bonn0 sites6 target enrollmentJuly 2, 2021
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Primary Progressive Aphasia (G31.0)
- Sponsor
- niversitätsklinikum Bonn
- Enrollment
- 6
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Written consent to participation in study
- •\- Patients who are able to follow instructions and are compliant with the frequent study visits
- •\- The patient is able to understand all verbal and written information
- •\- Clinically diagnosed PPA (mild to moderate) according to current diagnostic criteria
Exclusion Criteria
- •\- Patient does not consent to this study
- •\- Patient is not able to understand the extent, meaning nor the consequences of this clinical study
- •\- Patient is unable to follow the procedure of the study
- •\- Stable use of medication against dementia (\< 3 months)
- •\- Strong cognitive deficits (Mini\-Mental Status Test \<21\)
- •\- Acute psychotic episode
- •\- Neurological disorder apart from dementia being the reason for cognitive and/or language deficits (e.g. stroke, MS, Parkinson disease)
- •Comorbid language disorder that is not due to PPA, e.g. stroke
- •Exclusion criteria considering use of rTMS:
- •\- Standard inclusion and exclusion criteria of
Outcomes
Primary Outcomes
Not specified
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