WHETHER IL6 LEVELS IN CSF AIDS IN DIAGNOSIS OF NEONATAL MENINGITIS
Not Applicable
- Conditions
- Health Condition 1: G00- Bacterial meningitis, not elsewhere classified
- Registration Number
- CTRI/2024/04/065390
- Lead Sponsor
- DR NIVEDEETHA K
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Neonates less than 28 days of age
2. Clinical suspicion of sepsis
3. Indication for lumbar puncture as per unit protocol
Exclusion Criteria
1. Neonates who had received antibiotics for = 3 days
2. Recent brain surgery/ventricular tap
3. Moribound condition in which life expectancy less than 24hours
4. Grossly traumatic taps
5. Major congenital malformations – meningomyelocele /vertebral anamolies.
6. Presence of deep seated focus of infection other than meningitis e.g. abscess, septic arthritis etc.
7. Hemodynamic instability, bleeding disorder and coagulopathy.
8. Presence of infection at the lumbar puncture site.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cerebrospinal fluid analysis in neonates <br/ ><br>TERM newborn : WBC more than 8 cells And Glucose less than 20 mg/dl OR Protein more than 120mg/dl <br/ ><br>PRETERM: WBC more than 10 cells And Glucose less than 24mg/dl OR Protein more than 170mg/dl <br/ ><br>With or without CSF culture positivity.Timepoint: At baseline
- Secondary Outcome Measures
Name Time Method ILTimepoint: NI