Sarcopenia; a New Issue in Juvenile Idiopathic Arthritis
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 主要终点
- skeletal muscle mass
研究概览
简要总结
Juvenile idiopathic arthritis (AJI), is a frequent inflammatory disease in children, characterized by pain, arthritis, and deformities. Chronic inflammation leads to physical inactivity and can be associated with muscle weakness around affected joints, low bone strength, and mass(3). To our knowledge, no study has focused on the prevalence of sarcopenia in JIA and the data on the muscle disorder are lacking. The purpose of the present study is to detect sarcopenia and identify associated factors in children with JIA
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 4 Years 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •children with juvenile idiopathic arthritis fulfilling the ILAR criteria
排除标准
- •We excluded patients who have a prosthesis, nutritional problems, inflammatory bowel disease, coeliac disease, temporomandibular involvement, or another chronic disease.
结局指标
主要结局
skeletal muscle mass
时间窗: 4 months
Dual-energy X-ray absorptiometry (DXA) measures the appendicular lean mass ( the sum of the lean mass of the arms and legs) and adjusted to the body mass index
次要结局
- muscle strenght(5 months)
研究者
lassoued ferjani Hanene
Assistant professor
University Tunis El Manar