A Feasibility Study of a Physical Activity Intervention in Older Adult Inpatients With Acute Leukemia
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Leukemia
- Sponsor
- Wake Forest University Health Sciences
- Enrollment
- 26
- Locations
- 1
- Primary Endpoint
- Percentage of eligible patients recruited into the study
- Status
- Completed
- Last Updated
- 8 years ago
Overview
Brief Summary
RATIONALE: Physical activity sessions may help improve physical function, quality of life, and symptoms caused by chemotherapy in older patients with acute myelogenous leukemia.
PURPOSE: This clinical trial is studying how well physical activity works in improving quality of life in older patients with acute myelogenous leukemia undergoing chemotherapy.
Detailed Description
OBJECTIVES: Primary * To test the feasibility of conducting a physical activity intervention in hospitalized older adults with acute myeloid leukemia (AML) undergoing induction or reinduction chemotherapy. Secondary * To obtain preliminary data regarding the effectiveness of a physical activity intervention on physical function, quality of life, and treatment-related symptoms in these patients. OUTLINE: Patients undergo a baseline evaluation in week 1 focusing on basic demographics, health, physical function and quality-of-life assessments. These assessments include the Short Physical Performance Battery (SPPB); the Hand Grip Test of Muscular Strength; the Demographics and Physical Activity History; the Functional Assessment of Cancer Therapy (FACT-Leu); the Distress Thermometer; the Short-form Positive Affect Schedule (PANAS-SF); the Satisfaction with Life Scale (SWL); the FAST-23 Disability Measure; the Center for Epidemiologic Studies Depression Scale Short Form (CES-D); the Self-efficacy for Physical Activity Scale; the Intervention Feedback Form; and the Pre-Post Session Ratings. Some medical data may be obtained from the patient's medical record to assist in these assessments. Beginning in weeks 2-5, patients undergo a 30-minute orientation to the exercise sessions that will be tailored to individual needs and abilities. Patients undergo a 30- to 45-minute group physical activity session twice a week, and a supervised individual session following the same format as the group session, once a week for 4 weeks. After completion of the physical activity intervention, patients complete an activities packet and repeat the physical function and quality of life assessments in weeks 5-6 and again upon readmission for consolidation therapy in weeks 9-13 . After completion of study intervention, patients are followed for 4 months.
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Percentage of eligible patients recruited into the study
Time Frame: day 1
Percentage of study participants who successfully completed the physical and the psychosocial measures
Time Frame: week 13
Number and frequency of reported barriers to eligibility and enrollment
Time Frame: day 1
Percentage of adults 50 years of age or older admitted for induction or reinduction chemotherapy for acute myeloid leukemia (AML) who are eligible for the study
Time Frame: day 1
Record barriers to completion of the physical activity program
Time Frame: week 13
Secondary Outcomes
- Physical function as measured by the Short Physical Performance Battery (SPPB)(week 13)
- Quality of Life as measured with the Distress Thermometer(week 13)