A Feasibility Study of a Physical Activity Intervention in Older Adult Inpatients With Acute Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 26
- 试验地点
- 2
- 主要终点
- Percentage of eligible patients recruited into the study
研究概览
简要总结
RATIONALE: Physical activity sessions may help improve physical function, quality of life, and symptoms caused by chemotherapy in older patients with acute myelogenous leukemia.
PURPOSE: This clinical trial is studying how well physical activity works in improving quality of life in older patients with acute myelogenous leukemia undergoing chemotherapy.
详细描述
OBJECTIVES:
Primary
- To test the feasibility of conducting a physical activity intervention in hospitalized older adults with acute myeloid leukemia (AML) undergoing induction or reinduction chemotherapy.
Secondary
- To obtain preliminary data regarding the effectiveness of a physical activity intervention on physical function, quality of life, and treatment-related symptoms in these patients.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 120 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •DISEASE CHARACTERISTICS:
- •Histologically confirmed acute myeloid leukemia (AML) by WHO criteria
- •Planning to undergo induction or reinduction chemotherapy
- •Inpatient status at Wake Forest University Baptist Medical Center
- •Must not require intensive care unit support
- •PATIENT CHARACTERISTICS:
- •Able to understand English
- •Medical eligibility confirmed with Leukemia Service Attending
- •Ambulatory or able to walk with a cane
- •No hemodynamic instability
- •No acute thrombosis within the past 7 days
- •No active ischemia within the past 7 days
- •No uncontrolled pain
- •Must have < 3 incorrect responses on the Pfeiffer Mental Status Exam
- •PRIOR CONCURRENT THERAPY:
- •See Disease Characteristics
排除标准
- 未提供
结局指标
主要结局
Percentage of eligible patients recruited into the study
时间窗: day 1
Percentage of study participants who successfully completed the physical and the psychosocial measures
时间窗: week 13
Number and frequency of reported barriers to eligibility and enrollment
时间窗: day 1
Percentage of adults 50 years of age or older admitted for induction or reinduction chemotherapy for acute myeloid leukemia (AML) who are eligible for the study
时间窗: day 1
Record barriers to completion of the physical activity program
时间窗: week 13
次要结局
- Physical function as measured by the Short Physical Performance Battery (SPPB)(week 13)
- Quality of Life as measured with the Distress Thermometer(week 13)