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Clinical Trials/NCT01275924
NCT01275924
Completed
Not Applicable

Tightrope or Screw Fixation of Acute Tibiofibular Syndesmotic Injury. Randomised Controlled Trial.

Sykehuset Asker og Baerum2 sites in 1 country97 target enrollmentJanuary 2011

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Syndesmotic Injury of the Ankle
Sponsor
Sykehuset Asker og Baerum
Enrollment
97
Locations
2
Primary Endpoint
OTA Score (Modified American Orthopaedic Foot and Ankle Society ankle hind foot score)
Status
Completed
Last Updated
8 years ago

Overview

Brief Summary

Syndesmotic injuries are common and often associated with unstable ankle fractures. The most common treatment is with a syndesmotic screw through the fibula and tibia which is later removed, usually after 10-12 weeks. The Tightrope Syndesmosis Repair Kit (Arthrex; Naples, Florida). is used for the same indication, it consists of a heavy suture placed across the syndesmosis which has been looped and tightened through cortical button anchors on either side of the ankle. It does not need removal and thus avoids subsequent surgery. This trial compares these two treatment methods for syndesmotic injuries of the ankle.

Detailed Description

Patients 18-70 years presenting to one of the two hospitals with an acute syndesmotic injury are eligible for inclusion. 50 patients are randomised to two treatment groups: One group receives a Tightrope (R) fixation and the other receives a quadricortical screw fixation which is removed after 12 weeks. Follow-up intervals are at 6 weeks, 6, 12 and 24 months with standardised CT scans postoperatively and at 12, 24 months and 5 years clinical end-ponts/scores.

Registry
clinicaltrials.gov
Start Date
January 2011
End Date
April 2018
Last Updated
8 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Sykehuset Asker og Baerum
Responsible Party
Principal Investigator
Principal Investigator

Wender Figved

MD PhD

Sykehuset Asker og Baerum

Eligibility Criteria

Inclusion Criteria

  • 18 to 70 years
  • Acute syndesmotic injury with or without Weber type C fracture

Exclusion Criteria

  • Prior injury of the same ankle
  • Severe injury of same leg affecting rehabilitation
  • Symptomatic osteoarthritis of same ankle
  • Open injury
  • Decubital injury affecting surgical site
  • Dementia or unable to sign informed consent
  • Neuropathic conditions affecting same leg

Outcomes

Primary Outcomes

OTA Score (Modified American Orthopaedic Foot and Ankle Society ankle hind foot score)

Time Frame: 5 years

Modified American Orthopaedic Foot and Ankle Society ankle hind foot score (0-100)

Secondary Outcomes

  • Olerud-Molander Ankle (OMA) Score(5 years)
  • Health-related quality of life (EQ-5D)(5 years)
  • Dorsiflexion angle(5 years)
  • CT measurements of syndesmotic distance(5 years)

Study Sites (2)

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