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A phase II study of TSU-68 in patient with metastatic colorectal cancer

Phase 2
Conditions
Metastatic colorectal cancer
Registration Number
JPRN-jRCT2080221366
Lead Sponsor
Taiho Pharmaceutical Co., Ltd.
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
100
Inclusion Criteria

(1) Signed, written informed consent.
(2) Histologically or cytologically confirmed CRC.
(3) Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1.

Exclusion Criteria

(1) Brain metastasis or leptomeningeal metastasis confirmed by imaging study, or suspected brain metastasis.
(2) Presence of active infection.
(3) Known clinically significant interstitial lung disease or pulmonary fibrosis.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Progression free survival<br>RECIST (ver. 1.1)
Secondary Outcome Measures
NameTimeMethod
Overall response rate, Overall survival, Safety<br>CTCAE (ver. 4.0)
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