Perfusion index as a noninvasive parameter to measure hemodynamic response during larngoscopy in a patient posted under general anaesthesia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 70
- 试验地点
- 1
- 主要终点
- Measurement of hemodynamic response using perfusion index
研究概览
简要总结
The Perfusion Index (PI) is the ratio of the pulsatile to the non-pulsatile signal obtained from the pulse oximetry wave-form that is incorporated in several modern pulse oximeter monitors available in operating theatres.
It decreases with vasoconstriction and increases with vasodilatation, and several studies have suggested that the PI may be a sensitive estimate of the level of hemodynamic activity, as it indicates the status of the microcirculation which is densely innervated by sympathetic nerves, so our purpose is to check the findings of previous studies and to decide whether PI can be used as noninvasive parameter to measure hemodynamic response or not.
PI has been used to predict low blood pressure, identify early success indicators of central and peripheral nerve block effect assessment, evaluate systemic vascular resistance, indicate the success of sympathectomy and identify the incidence of hypotension after spinal anaesthesia
In our study ,We will check PI as non invasive parameter for hemodynamic response with the help of changes in perfusion index during Laryngoscopy
Recruitment of patients will start after the CTRI registration
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •ASA I AND II Type Of Surgery-surgical procedure requiring general anaesthesia mallampati score 1 and 2 , upper lip bite test class 1 , hyomental distance greater than 6 cm.
- •CLS Grade 1 only.
排除标准
- •patient refusal parturient females patients with any neuromuscular disorder patients with any renal , hepatic disease , IHD and hypertension with/without treatment BMI greater than 30 kg/m2 known hypersensitivity to drugs used in our study mallampati score III/IV difficult intubation :- impending / expected difficult intubation ( Predicted ) patient who gives H/O previous difficult intubation.
结局指标
主要结局
Measurement of hemodynamic response using perfusion index
时间窗: baseline 0 minutes,during laryngoscopy - at the time of intubation , post intubation for 10 minutes, before reversal , during laryngoscopy- at the time of extubation ,post extubation for 10 minutes
次要结局
- correlate change in hemodynamic parameters with perfusion index(baseline 0 minutes,during laryngoscopy - at the time of intubation , post intubation for 10 minutes, before reversal , during laryngoscopy- at the time of extubation ,post extubation for 10 minutes)
研究者
VRAJ SHAH
Surat municipal institute of medical education and research