Skip to main content
Clinical Trials/CTRI/2025/02/079905
CTRI/2025/02/079905
Completed
Not Applicable

Perfusion index as a noninvasive parameter to measure hemodynamic response during larngoscopy in a patient posted under general anaesthesia

dr vraj shah1 site in 1 country70 target enrollmentStarted: February 20, 2025Last updated:

Overview

Phase
Not Applicable
Status
Completed
Sponsor
dr vraj shah
Enrollment
70
Locations
1
Primary Endpoint
Measurement of hemodynamic response using perfusion index

Overview

Brief Summary

The Perfusion Index (PI) is the ratio of the pulsatile to the non-pulsatile signal obtained from the pulse oximetry wave-form that is incorporated in several modern pulse oximeter monitors available in operating theatres.

It decreases with vasoconstriction and increases with vasodilatation, and several studies have suggested that the PI may be a sensitive estimate of the level of hemodynamic activity, as it indicates the status of the microcirculation which is densely innervated by sympathetic nerves, so our purpose is to check the findings of previous studies and to decide whether PI can be used as noninvasive parameter to measure hemodynamic response or not.

PI has been used to predict low blood pressure, identify early success indicators of central and peripheral nerve block effect assessment, evaluate systemic vascular resistance, indicate the success of sympathectomy and identify the incidence of hypotension after spinal anaesthesia

In our study ,We will check PI as non invasive parameter for hemodynamic response with the help of changes in perfusion index during Laryngoscopy

Recruitment of patients will start after the CTRI registration

Study Design

Study Type
Interventional
Allocation
Na
Masking
None

Eligibility Criteria

Ages
18.00 Year(s) to 60.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • ASA I AND II Type Of Surgery-surgical procedure requiring general anaesthesia mallampati score 1 and 2 , upper lip bite test class 1 , hyomental distance greater than 6 cm.
  • CLS Grade 1 only.

Exclusion Criteria

  • patient refusal parturient females patients with any neuromuscular disorder patients with any renal , hepatic disease , IHD and hypertension with/without treatment BMI greater than 30 kg/m2 known hypersensitivity to drugs used in our study mallampati score III/IV difficult intubation :- impending / expected difficult intubation ( Predicted ) patient who gives H/O previous difficult intubation.

Outcomes

Primary Outcomes

Measurement of hemodynamic response using perfusion index

Time Frame: baseline 0 minutes,during laryngoscopy - at the time of intubation , post intubation for 10 minutes, before reversal , during laryngoscopy- at the time of extubation ,post extubation for 10 minutes

Secondary Outcomes

  • correlate change in hemodynamic parameters with perfusion index(baseline 0 minutes,during laryngoscopy - at the time of intubation , post intubation for 10 minutes, before reversal , during laryngoscopy- at the time of extubation ,post extubation for 10 minutes)

Investigators

Sponsor
dr vraj shah
Sponsor Class
Other [self]
Responsible Party
Principal Investigator
Principal Investigator

VRAJ SHAH

Surat municipal institute of medical education and research

Study Sites (1)

Loading locations...

Similar Trials