The anti-bradycardia effect of intramuscular Ephedrine injection in combined spinal-anesthesia and dexmedetomidine sedation : a randomized, double-blind, placebo-controlled study
- Conditions
- Not Applicable
- Registration Number
- KCT0002833
- Lead Sponsor
- Yonsei University, Wonju Severance Christian Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 120
Patients scheduled to undergo spinal anesthesia for sedation
Under 20
- American Society of Anesthesiology grade 3 or higher
-Norepinephrine A person taking a reuptake inhibitor. (Eg, tricyclic antidepressants, monoamine
oxidase inhibitors, acute cocaine intoxication)
- myocardial infarction and stroke within the past one year
- Prior to major cardiac surgery within 1 year
- Patients diagnosed with heart failure
- Patients who require vasodilators or oxygen therapy because they are anxious before surgery.
- Patients with fever (> 38 degrees)
- Patients with medication-sensitive history of previous sedation.
- Severe Uncontrolled High Blood Pressure (systolic blood pressure >180, diastolic blood pressure >100)
- Patients who can not talk and have cognitive impairment
- If the subject includes a person who can not read the consent form (eg, illiterate, foreigner, etc.)
- You have received other treatment or surgery.
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Occurrence of bradycardia (under 50 heart beats per minute) during dexmedetomidine sedation
- Secondary Outcome Measures
Name Time Method Frequency of hypotension;occurence of bradycardia;Occurence of hypotension