Effect of Retrograde Autologous Blood Priming on Pulmonary Mechanics in Pediatric Cardiac Surgery
Not Applicable
Completed
- Conditions
- Congenital Heart Disease
- Interventions
- Procedure: Pediatric cardiac surgery
- Registration Number
- NCT04260204
- Lead Sponsor
- Ain Shams University
- Brief Summary
The present study hypothesized that beyond its hemodynamic affects,retrograde autologus blood priming of cardiopulmonary bypass (RAP) has a positive impact on hemodynamics and pulmonary mechanics subjected to cardiac surgery.
- Detailed Description
This prospective randomized study analyzed the clinical records of 124 children subjected to cardiac surgery for congenital heart diseases with left to right shunt. They comprised 64 patients with RAP and 60 patients conventional cardiopulmonary bypass priming. The preoperative, intraoperative and postoperative data of the studied patients were reported.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 124
Inclusion Criteria
- children complained of congenital heart disease with left to right shunt pressure or volume load
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Exclusion Criteria
- cyanotic heart disease
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Retrograde priming Pediatric cardiac surgery retrograde autologous Blood Priming of Cardiopulmonary Bypass (RAP) in young children subjected to cardiac surgery for congenital heart defects with left to right shunt associated with volume or pressure overload. conventional priming Pediatric cardiac surgery conventional cardiopulmonary priming in young children subjected to cardiac surgery for congenital heart defects with left to right shunt associated with volume or pressure overload.
- Primary Outcome Measures
Name Time Method Comparison of postoperative peak air way pressure between the studied groups 1 hour after surgery peak air way pressure (Paw) in cmH2O
Comparison of postoperative air way resistance between the studied groups 1 hour after surgery air way resistance (Raw) in cmH2O/L/sec.
Comparison of postoperative Plateau pressure between the studied groups 1 hour after surgery Plateau pressure in cm H2O
Comparison of postoperative Lung compliance between the studied groups 1 hour after surgery Lung compliance in L/cm H2O
Comparison of postoperative Tidal volume between the studied groups 1 hour after surgery Tidal volume in ml
- Secondary Outcome Measures
Name Time Method