Effect of Retrograde Autologous Blood Priming of Cardiopulmonary Bypass on Hemodynamic Parameters and Pulmonary Mechanics in Pediatric Cardiac Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Congenital Heart Disease
- Sponsor
- Ain Shams University
- Enrollment
- 124
- Primary Endpoint
- Comparison of postoperative peak air way pressure between the studied groups
- Status
- Completed
- Last Updated
- 6 years ago
Overview
Brief Summary
The present study hypothesized that beyond its hemodynamic affects,retrograde autologus blood priming of cardiopulmonary bypass (RAP) has a positive impact on hemodynamics and pulmonary mechanics subjected to cardiac surgery.
Detailed Description
This prospective randomized study analyzed the clinical records of 124 children subjected to cardiac surgery for congenital heart diseases with left to right shunt. They comprised 64 patients with RAP and 60 patients conventional cardiopulmonary bypass priming. The preoperative, intraoperative and postoperative data of the studied patients were reported.
Investigators
Dr. Hamdy Singab
Professor
Ain Shams University
Eligibility Criteria
Inclusion Criteria
- •children complained of congenital heart disease with left to right shunt pressure or volume load
Exclusion Criteria
- •cyanotic heart disease
Outcomes
Primary Outcomes
Comparison of postoperative peak air way pressure between the studied groups
Time Frame: 1 hour after surgery
peak air way pressure (Paw) in cmH2O
Comparison of postoperative air way resistance between the studied groups
Time Frame: 1 hour after surgery
air way resistance (Raw) in cmH2O/L/sec.
Comparison of postoperative Plateau pressure between the studied groups
Time Frame: 1 hour after surgery
Plateau pressure in cm H2O
Comparison of postoperative Lung compliance between the studied groups
Time Frame: 1 hour after surgery
Lung compliance in L/cm H2O
Comparison of postoperative Tidal volume between the studied groups
Time Frame: 1 hour after surgery
Tidal volume in ml