The EndoChill Trial: Evaluating the safety and efficacy of the Wim Hof Method for endometriosis pai

Not Applicable

• Conditions: Endometriosis; Endometriosis-associated pain; Alternative and Complementary Medicine - Other alternative and complementary medicine; Reproductive Health and Childbirth - Other reproductive health and childbirth disorders; Reproductive Health and Childbirth - Menstruation and menopause

• Registration Number: ACTRN12624000950561
• Lead Sponsor: The University of Adelaide

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-05
• Last Update Posted: 12 August 2024

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Female
• Target Recruitment: 32

Inclusion Criteria

Diagnosis of endometriosis (according to European Society and Human Reproduction and Embryology (ESHRE) guidelines)
Endometriosis lesions visible on eTVUS scan
Aged 18 years or older
Rate average period pain over past two menstrual cycles as at least 3/10 on an 11-point numerical rating scale (NRS)

Exclusion Criteria

Health conditions contraindicating participation in WHM training (e.g., coronary heart disease, cold urticaria etc.)
Are pregnant
Have had surgery in the past 6 months
Are intending to have surgery (e.g., laparoscopy for endometriosis) over the duration of the trial

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pelvic pain[11-point numerical rating scale (NRS) for pelvic pain answered daily by participants using the Ethica app. Participants to register daily pelvic pain scores for the study duration (baseline, intervention, and follow-up phases).];Pelvic pain lifestyle impact[Pelvic Pain Impact Questionnaire (PPIQ) answered by participants using the Ethica app. PPIQ completed once at baseline, mid-intervention (intervention week 6), end-intervention (intervention week 12) and follow-up (8 weeks post-intervention phase).];Pelvic pain psychological impact[Pelvic Pain Psychological Screening Questionnaire (3PSQ) answered by participants using the Ethica app. 3PSQ completed once at baseline, mid-intervention (intervention week 6), end-intervention (intervention week 12) and follow-up (8 weeks post-intervention phase).]