Fatigue and function of platelets in patients with chronic ITP
- Conditions
- chronic ITPplatelet functionImmune thrombocytopeniafatigue
- Registration Number
- NL-OMON26409
- Lead Sponsor
- niversity Medical Center Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Age 16 years and older
-Previously confirmed diagnosis of chronic primary ITP with current platelet counts of <100x109/L or currently on (any) treatment for chronic ITP
-Willing and able to understand the study information and sign the informed consent form.
Exclusion Criteria
There are no additional exclusion criteria
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess platelet function and coagulation parameters in adult chronic ITP patients in relation to their bleeding phenotype
- Secondary Outcome Measures
Name Time Method -To assess immune profiles in chronic ITP patients and explore for imbalances between effector cells and regulatory cells<br /><br>-To validate the CIS-20 fatigue subscale in chronic ITP patients by comparing it to the FACIT-F<br /><br>-To assess the prevalence of menorrhagia in female chronic IT patients and the impact on daily life<br /><br>-To compare fatigue in chronic ITP patients with fatigue in healthy controls and other chronically ill patients