Analysis of Anti-inflammatory and Antioxidant Pathways in Lung Diseases by Haem Oxygenase-1 (HO-1) in Induced Sputum and Carbon Monoxide (CO) in Exhaled Air

• Conditions: Lung Diseases

• Registration Number: NCT01140685
• Lead Sponsor: Tel-Aviv Sourasky Medical Center

Brief Summary

This work will focus on the anti-inflammatory and antioxidant pathways in lung diseases by measuring HO-1 in induced sputum and CO in exhaled air in cases of four respiratory diseases, asthma, chronic obstructive pulmonary disease (COPD), occupational lung diseases (OLD) and interstitial lung disease (ILD).

Detailed Description

Not available

Study Timeline

• Study Start: 2009-12
• Study First Submitted: 2010-02-17
• Status Verified: 2010-03
• Study First Submitted QC: 2010-06-08
• Last Update Submitted: 2010-06-08
• Study First Posted: 2010-06-09
• Last Update Posted: 2010-06-09
• Primary Completion: 2010-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

• Male and female
• Ages >/= 18 years
• Diagnosed with one or more lung diseases
• Referred for sputum induction to the Pulmonary Laboratory in the Tel-Aviv Sourasky Medical Center

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
exhaled CO levels	2010-2011