A Psoriasis Plaque Test Comparing Products for the Treatment of Psoriasis Vulgaris

Phase 1

Completed

• Conditions: Psoriasis Vulgaris
• Interventions: Drug: Combination of clobetasol propionate plus calcipotriol ointment, clobetasol propionate ointment, calcipotriol ointment, and the ointment vehicle

• Registration Number: NCT01043224
• Lead Sponsor: LEO Pharma

Brief Summary

The purpose of this trial is to compare the anti-psoriatic effect of a topical combination product containing clobetasol propionate and calcipotriol in an ointment formulation to the single components in the same vehicle using a psoriasis plaque test design.

Detailed Description

Not available

Study Timeline

• Study Start: 2010-01
• Study First Submitted: 2010-01-05
• Study First Submitted QC: 2010-01-05
• Study First Posted: 2010-01-06
• Primary Completion: 2010-03
• Study Completion: 2010-03
• Status Verified: 2013-10
• Last Update Submitted: 2025-02-21
• Last Update Posted: 2025-02-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Clobetasol propionate plus calcipotriol	Combination of clobetasol propionate plus calcipotriol ointment, clobetasol propionate ointment, calcipotriol ointment, and the ointment vehicle	-

Primary Outcome Measures

Name	Time	Method
Total Clinical Score of clinical symptoms	3 weeks

Secondary Outcome Measures

Name	Time	Method
Clinical scores, lesions thickness, NIR spectroscopic measurements	3 weeks

Trial Locations

Locations (1)

LEO Pharma investigational site; 🇫🇷 Nice, France