T cell responses after yellow fever and other vaccinations

Recruiting

• Conditions: Z23; Z24; Z25; Need for immunization against single bacterial diseases; Need for immunization against certain single viral diseases; Need for immunization against other single viral diseases

• Registration Number: DRKS00034356
• Lead Sponsor: niversitätsklinikum Erlangen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 2022-10-04
• Study Start: 2024-05-29
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 200

Inclusion Criteria

Vaccination with the vaccine for which the immune responses is to be investigated

Exclusion Criteria

a) Incapable of giving consent
b) Minors
c) Pregnant or breastfeeding women
d) Persons who are in a dependent relationship with other study participants or the study investigators

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antigen specificity (determined based on the binding of pMHC multimers), RNA transcriptome, T cell receptor sequence, HLA status

Secondary Outcome Measures

Name	Time	Method
Antigen-specific T cell response size