Micro-elimination of Hepatitis C in a Rural Appalachian Community: The Implementation and Expansion of an Innovative Collaborative Care Model of Telehealth and Knowledge Sharing Focusing on People Who Inject Drugs
试验速览
- 阶段
- 不适用
- 入组人数
- 300
- 主要终点
- Cohort-level Hepatitis C Treatment Progress
研究概览
简要总结
The objective of this protocol is to conduct a comprehensive quantitative and qualitative assessment of the impact of our innovative collaborative telehealth HCV care model on patient treatment experiences and quality of life.
详细描述
The investigators will evaluate the proportion of patients at each step of the HCV care cascade before and after implementation of the collaborative care model. Additionally, participants will complete questionnaires at three time points: at the initiation of hepatitis C treatment, at treatment completion, and at the assessment of sustained virologic response. Questionnaires will assess quality of life, mental health, chronic liver disease outcomes, and substance use. A subset of participants will also complete semi-structured interviews at each of the three time points. Then, a smaller subset of participants will be selected for a detailed ethnographic case study focusing on treatment experiences, quality of life, forms of social support, and illness experience.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years or older
- •Detectable HCV viral load
- •Attended a clinic appointment at one of our participating sites
排除标准
- •Cognitive disability such that informed consent cannot be obtained
- •Prisoners
- •Unable to understand English
结局指标
主要结局
Cohort-level Hepatitis C Treatment Progress
时间窗: 12 months
Change in the proportion of patients at each step of the HCV care continuum (linkage to care, treatment initiation, treatment completion and sustained virologic suppression) before and after program implemenation
次要结局
- Patient Reported Quality-of-Life(12 months)
- Depression(12 months)
- Semi-Structured Qualitative Interview about Impact of HCV Treatment(12 months)
- Health-Related Quality-of-Life(12 months)
研究者
Rebecca Dillingham, MD/MPH
Director of the Center for Global Health
University of Virginia
