Evaluation of the Efficacy of Selecta Laser Trabeculoplasty in Patients Undergoing Filtering Surgery
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 75
- 试验地点
- 1
- 主要终点
- Change of the intraocular pressure after surgery
研究概览
简要总结
Glaucoma is a common, potentially blinding pathology, threatening patients' autonomy and quality of life. The main aim of treatment is to lower intraocular pressure (IOP) in order to slow nerve fiber loss as much as possible, leading to alterations in the visual field and even reduced visual acuity. To achieve this drop in pressure, there are, of course, hypotonizing eye drops, trabeculoplasty with Laser Selecta (SLT) or filtering surgery (trabeculectomy, deep non-perforating sclerectomy, insertion of drainage devices). Laser Selecta specifically targets pigmented trabecular meshwork cells without damaging adjacent structures, and is thought to act via three mechanisms: distension of Schlemm's canal, reorganization of trabecular meshwork cells and stimulation of extracellular matrix production. Its efficacy has been demonstrated in several studies, with a 20-30% reduction in intraocular pressure in patients who have never undergone surgery. Few studies have investigated the efficacy of SLT in patients who have already undergone filtering surgery. The aim of this study is therefore to determine the efficacy of SLT in previously operated patients whose intraocular pressure remains insufficiently controlled.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients aged ≥ 18 years
- •Patients who have undergone filtering surgery such as trabeculectomy, deep non-perforating sclerectomy, or placement of a Xen®-type device
- •Patients who have undergone laser SLT
- •Patient with primary open-angle glaucoma, exfoliative glaucoma or pigmentary glaucoma
- •Insufficiently controlled intraocular pressure.
排除标准
- •Patients under guardianship or curatorship
- •Patient deprived of liberty
- •Patient objecting to the use of his or her data for this research
- •Patient with angle-closure glaucoma
- •Patient having undergone any other type of eye surgery except cataract surgery
结局指标
主要结局
Change of the intraocular pressure after surgery
时间窗: 12 months
Intraocular pressure is measured before procedure , 1 month, 6months and 12 months after procedure
次要结局
- Average change of the intraocular pressure after procedure depending on the type of filtering surgery(12 months)
- Average change of the intraocular pressure after procedure depending of the initial IOP(12 months)
- Average change of the intraocular pressure after procedure depending on the delay between filtering surgery and the Selecta Laser procedure.(12 months)
- Average change of the intraocular pressure after procedure depending on the type of glaucoma(12 months)
