NCT00360763Unknown4 期
Study of Optimal Treatment Plan in Hypertensives With Anti-AT1-Receptor Autoantibody
适应症
相关药物
试验速览
- 阶段
- 4 期
- 入组人数
- 600
- 试验地点
- 1
研究概览
简要总结
The autoantibodies against AT1 receptor (ATR-AA), behaving like an agonist were detected in patients with hypertension. ATR-AA which can blocked by ARB may play a role in the pathogenesis of hypertension. The present study is to explore whether AT1 receptor blocker has superior anti-hypertensive effect in patients with positive ATR-AA hypertension. Patients with 2 grade hypertension were recruited and ATR-AA was assayed by ELISA. A study was carried out and the efficacy of anti-hypertension was compared between candesartan cilexetil and ACE inhibitor imidapril.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Hypertension (2 grade)
排除标准
- •Secondary hypertension
- •Known sensitivity or intolerance to an angiotensin II receptor antagonist or ACE inhibitor
- •Pregnancy
研究者
研究点 (1)
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