Evaluating The Effects of Probiotics on Symptoms of Patients With Irritable Bowel Syndrome
Overview
- Phase
- Phase 2
- Intervention
- Probiotic
- Conditions
- Irritable Bowel Syndrome
- Sponsor
- Isfahan University of Medical Sciences
- Enrollment
- 132
- Locations
- 1
- Primary Endpoint
- Abdominal pain
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
Evidence have shown benefits of gut flora modulation in treatment of irritable bowel syndrome (IBS), but few reports are available on the effects of multistrain probiotics and there are few reports available in this regard from our society. Thus, we investigated if probiotics are effective in our patients as well. We hypothesize that the multistrain probiotic Balance containing seven bacteria species including Lactobacillus strains, Bifidobacterium strains, and Streptococcus thermophiles reduces the symptoms of irritable bowel syndrome.
Investigators
Ali Gholamrezaei
Dr.
Isfahan University of Medical Sciences
Eligibility Criteria
Inclusion Criteria
- •age between 18 and 65
- •diagnosis of IBS based on the Rome III criteria
- •willingness to participate
Exclusion Criteria
- •receiving other probiotics compound during the study
- •receiving antibiotics during the study
Arms & Interventions
Probiotic
Intervention: Probiotic
Placebo
Intervention: Placebo
Outcomes
Primary Outcomes
Abdominal pain
Time Frame: Up to 6 weeks
Abdominal pain was assessed by Rome III questionnaire at baseline and then after 6 weeks
Secondary Outcomes
- Quality of Life(Up to 6 weeks)