Evaluating The Effects of Probiotics on Symptoms of Patients With Irritable Bowel Syndrome
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 132
- 试验地点
- 1
- 主要终点
- Abdominal pain
研究概览
简要总结
Evidence have shown benefits of gut flora modulation in treatment of irritable bowel syndrome (IBS), but few reports are available on the effects of multistrain probiotics and there are few reports available in this regard from our society. Thus, we investigated if probiotics are effective in our patients as well. We hypothesize that the multistrain probiotic Balance containing seven bacteria species including Lactobacillus strains, Bifidobacterium strains, and Streptococcus thermophiles reduces the symptoms of irritable bowel syndrome.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age between 18 and 65
- •diagnosis of IBS based on the Rome III criteria
- •willingness to participate
排除标准
- •receiving other probiotics compound during the study
- •receiving antibiotics during the study
研究组 & 干预措施
Probiotic
干预措施: Probiotic (Drug)
Placebo
干预措施: Placebo (Drug)
结局指标
主要结局
Abdominal pain
时间窗: Up to 6 weeks
Abdominal pain was assessed by Rome III questionnaire at baseline and then after 6 weeks
次要结局
- Quality of Life(Up to 6 weeks)
研究者
Ali Gholamrezaei
Dr.
Isfahan University of Medical Sciences