Effect of high oxygen concentration on Surgical site infection in patients undergoing elective colorectal surgery
Phase 3
- Conditions
- Health Condition 1: null- Patients undergoing elective colorectal surgery under GA
- Registration Number
- CTRI/2017/09/009726
- Lead Sponsor
- Jawahar lal Institute of Postgraduate Education and Research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 200
Inclusion Criteria
All patients >18 years undergoing elective colorectal surgery under general anaesthesia
Exclusion Criteria
1.Minor colorectal procedures including polypectomy where the expected duration of surgery is less than one hour
2.Recent h/o fever, patient with known immunological dysfunction (on steroids, decompensated liver disease, HIV,)
3.Evidence of infection (TLC < 2500 or > 12000)
4.Emergency colorectal surgeries done for bowel obstruction
5.Severe malnutrition (albumin < 2.5 gm %)
6.Significant co-morbidities- unfit for G A.
7.Respiratory illness- COPD, asthma
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Surgical site infection postoperatively (according to the CDC criteria up to 30 days)Timepoint: 30 days
- Secondary Outcome Measures
Name Time Method A.Day of detection of SSI <br/ ><br>B.Grade of SSI (superficial incisional, deep incisional, organ space) <br/ ><br>C.Incidence and rate of anastomotic leak and day of detection of leak <br/ ><br>D.Immediate and early postoperative pain: at 24 hours after surgery and after one week <br/ ><br>E.Post op analgesic requirement: number of doses, drug/ route <br/ ><br>F.Return of bowel sound: perception of bowel movements or passage of flatus <br/ ><br>G.Day of patient ambulation <br/ ><br>H.Length of hospitalisation: in days <br/ ><br>Timepoint: 30 days