The effect of Dexmedetomidine on nausea and vomiting in Discectomy surgery
Phase 3
- Conditions
- ausea and vomiting due to Discectomy under spinal anesthesia.
- Registration Number
- IRCT20160307026950N35
- Lead Sponsor
- Esfahan University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
Patients 18 to 60 years
Candidate for Discectomy under spinal anesthesia
Grade 1 and 2 Anesthesia Based on American Society Anesthesia Criteria
Exclusion Criteria
History of cardiovascular, respiratory, neurological, endocrine, thyroid, neuromuscular diseases, dysautonomia
Fever
Obesity (BMI> 27)
History of vasoactive drugs, MAOI and TCA
History of drug use
Allergy to Pethidine, Ketamine and Magnesium sulfate
Pregnancy
Allergy to Dexmedetomidine
Taking drugs with drug interactions with Dexmedetomidine
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ausea and vomiting due to dexmedetomidine injection. Timepoint: Immediately after spinal up to 24 hours after surgery. Method of measurement: Use Visual Analogue Scale or VAS.
- Secondary Outcome Measures
Name Time Method Heart Rate. Timepoint: Immediately after spinal up to 24 hours after surgery. Method of measurement: ECG monitoring.;Systolic blood pressure. Timepoint: Immediately after spinal up to 24 hours after surgery. Method of measurement: Barometer.;Diastolic blood pressure. Timepoint: Immediately after spinal up to 24 hours after surgery. Method of measurement: Barometer.;Arterial blood oxygen saturation. Timepoint: Immediately after spinal up to 24 hours after surgery. Method of measurement: Pulse oximeter.